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How a β-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties.
J Med Chem. 2014 Oct 23;57(20):8563-75. doi: 10.1021/jm5010754. Epub 2014 Oct 14.
J Med Chem. 2014.
PMID: 25268757
New azepino[4,3-b]indole derivatives as nanomolar selective inhibitors of human butyrylcholinesterase showing protective effects against NMDA-induced neurotoxicity.
de Candia M, Zaetta G, Denora N, Tricarico D, Majellaro M, Cellamare S, Altomare CD.
de Candia M, et al. Among authors: zaetta g.
Eur J Med Chem. 2017 Jan 5;125:288-298. doi: 10.1016/j.ejmech.2016.09.037. Epub 2016 Sep 13.
Eur J Med Chem. 2017.
PMID: 27688184
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New organic nitrate-containing benzyloxy isonipecotanilide derivatives with vasodilatory and anti-platelet activity.
de Candia M, Marini E, Zaetta G, Cellamare S, Di Stilo A, Altomare CD.
de Candia M, et al. Among authors: zaetta g.
Eur J Pharm Sci. 2015 May 25;72:69-80. doi: 10.1016/j.ejps.2015.03.004. Epub 2015 Mar 10.
Eur J Pharm Sci. 2015.
PMID: 25769522
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