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Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint.
Sha SK, Sato T, Kobayashi H, Ishigaki M, Yamamoto S, Sato H, Takada A, Nakajyo S, Mochizuki Y, Friedman JM, Cheng FC, Okura T, Kimura R, Kufe DW, Vonhoff DD, Kawabe T. Sha SK, et al. Among authors: friedman jm. Mol Cancer Ther. 2007 Jan;6(1):147-53. doi: 10.1158/1535-7163.MCT-06-0371. Mol Cancer Ther. 2007. PMID: 17237275
CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity.
Sakakibara K, Saito N, Sato T, Suzuki A, Hasegawa Y, Friedman JM, Kufe DW, Vonhoff DD, Iwami T, Kawabe T. Sakakibara K, et al. Among authors: friedman jm. Blood. 2011 Oct 6;118(14):3922-31. doi: 10.1182/blood-2011-01-333138. Epub 2011 Aug 12. Blood. 2011. PMID: 21841164 Free article.
Real-world diagnostic outcomes and cost-effectiveness of genome-wide sequencing for developmental and seizure disorders: Evidence from Canada.
Regier DA, Loewen R, Chan B, Ehman M, Pollard S, Friedman JM, Stockler-Ipsiroglu S, van Karnebeek C, Race S, Elliott AM, Dragojlovic N, Lynd LD, Weymann D. Regier DA, et al. Among authors: friedman jm. Genet Med. 2024 Apr;26(4):101069. doi: 10.1016/j.gim.2024.101069. Epub 2024 Jan 8. Genet Med. 2024. PMID: 38205742 Free article.
Should secondary pharmacogenomic variants be actively screened and reported when diagnostic genome-wide sequencing is performed in a child?
Friedman JM, Bombard Y, Carleton B, Issa AM, Knoppers B, Plon SE, Rahimzadeh V, Relling MV, Williams MS, van Karnebeek C, Vears D, Cornel MC; Global Alliance for Genomics and Health Regulatory and Ethics Workstream. Friedman JM, et al. Genet Med. 2024 Feb;26(2):101033. doi: 10.1016/j.gim.2023.101033. Epub 2023 Nov 23. Genet Med. 2024. PMID: 38007624 Free article.
830 results