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The lectin BJcuL induces apoptosis through TRAIL expression, caspase cascade activation and mitochondrial membrane permeability in a human colon adenocarcinoma cell line.
Damasio Dde C, Nolte S, Polak LP, Brandt AP, Bonan NB, Zischler L, Stuelp-Campelo PM, Cadena SM, Noronha Ld, Elífio-Esposito SL, Moreno-Amaral AN. Damasio Dde C, et al. Among authors: elifio esposito sl. Toxicon. 2014 Nov;90:299-307. doi: 10.1016/j.toxicon.2014.08.062. Epub 2014 Sep 3. Toxicon. 2014. PMID: 25194746
BJcuL, a lectin purified from Bothrops jararacussu venom, induces apoptosis in human gastric carcinoma cells accompanied by inhibition of cell adhesion and actin cytoskeleton disassembly.
Nolte S, de Castro Damasio D, Baréa AC, Gomes J, Magalhães A, Mello Zischler LF, Stuelp-Campelo PM, Elífio-Esposito SL, Roque-Barreira MC, Reis CA, Moreno-Amaral AN. Nolte S, et al. Among authors: elifio esposito sl. Toxicon. 2012 Jan;59(1):81-5. doi: 10.1016/j.toxicon.2011.10.012. Epub 2011 Nov 4. Toxicon. 2012. PMID: 22079298 Free article.
Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.
Iessi E, Zischler L, Etringer A, Bergeret M, Morlé A, Jacquemin G, Morizot A, Shirley S, Lalaoui N, Elifio-Esposito SL, Fais S, Garrido C, Solary E, Micheau O. Iessi E, et al. Among authors: elifio esposito sl. PLoS One. 2015 May 26;10(5):e0126526. doi: 10.1371/journal.pone.0126526. eCollection 2015. PLoS One. 2015. PMID: 26010871 Free PMC article.
Antitumoral effects of Amblyomma sculptum Berlese saliva in neuroblastoma cell lines involve cytoskeletal deconstruction and cell cycle arrest.
Nascimento TGD, Vieira PS, Cogo SC, Dias-Netipanyj MF, França Junior N, Câmara DAD, Porcacchia AS, Mendonça RZ, Moreno-Amaral AN, Sá Junior PL, Simons SM, Zischler L, Elifio-Esposito S. Nascimento TGD, et al. Rev Bras Parasitol Vet. 2019 Jan-Mar;28(1):126-133. doi: 10.1590/S1984-296120180098. Epub 2019 Feb 14. Rev Bras Parasitol Vet. 2019. PMID: 30785557 Free article.
Neutrophils activated by BJcuL, a C-type lectin isolated from Bothrops jararacussu venom, decrease the invasion potential of neuroblastoma SK-N-SH cells in vitro.
Carneiro-Goetten JOL, Rodrigues BS, Nogoceke RA, do Nascimento TG, Moreno-Amaral AN, Stuelp-Campelo PM, Elifio-Esposito S. Carneiro-Goetten JOL, et al. J Venom Anim Toxins Incl Trop Dis. 2020 May 11;26:e20190073. doi: 10.1590/1678-9199-JVATITD-2019-0073. eCollection 2020. J Venom Anim Toxins Incl Trop Dis. 2020. PMID: 32425992 Free PMC article.
23 results