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Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.
Risolino M, Mandia N, Iavarone F, Dardaei L, Longobardi E, Fernandez S, Talotta F, Bianchi F, Pisati F, Spaggiari L, Harter PN, Mittelbronn M, Schulte D, Incoronato M, Di Fiore PP, Blasi F, Verde P. Risolino M, et al. Among authors: spaggiari l. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3775-84. doi: 10.1073/pnas.1407074111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157139 Free PMC article.
Alterations of the Notch pathway in lung cancer.
Westhoff B, Colaluca IN, D'Ario G, Donzelli M, Tosoni D, Volorio S, Pelosi G, Spaggiari L, Mazzarol G, Viale G, Pece S, Di Fiore PP. Westhoff B, et al. Among authors: spaggiari l. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22293-8. doi: 10.1073/pnas.0907781106. Epub 2009 Dec 10. Proc Natl Acad Sci U S A. 2009. PMID: 20007775 Free PMC article.
Immunhistochemistry by means of widely agreed-upon markers (cytokeratins 5/6 and 7, p63, thyroid transcription factor-1, and vimentin) on small biopsies of non-small cell lung cancer effectively parallels the corresponding profiling and eventual diagnoses on surgical specimens.
Pelosi G, Rossi G, Bianchi F, Maisonneuve P, Galetta D, Sonzogni A, Veronesi G, Spaggiari L, Papotti M, Barbareschi M, Graziano P, Decensi A, Cavazza A, Viale G. Pelosi G, et al. Among authors: spaggiari l. J Thorac Oncol. 2011 Jun;6(6):1039-49. doi: 10.1097/JTO.0b013e318211dd16. J Thorac Oncol. 2011. PMID: 21512408 Free article.
miR-Test: a blood test for lung cancer early detection.
Montani F, Marzi MJ, Dezi F, Dama E, Carletti RM, Bonizzi G, Bertolotti R, Bellomi M, Rampinelli C, Maisonneuve P, Spaggiari L, Veronesi G, Nicassio F, Di Fiore PP, Bianchi F. Montani F, et al. Among authors: spaggiari l. J Natl Cancer Inst. 2015 Mar 19;107(6):djv063. doi: 10.1093/jnci/djv063. Print 2015 Jun. J Natl Cancer Inst. 2015. PMID: 25794889
Sensitive and affordable diagnostic assay for the quantitative detection of anaplastic lymphoma kinase (ALK) alterations in patients with non-small cell lung cancer.
Dama E, Tillhon M, Bertalot G, de Santis F, Troglio F, Pessina S, Passaro A, Pece S, de Marinis F, Dell'Orto P, Viale G, Spaggiari L, Di Fiore PP, Bianchi F, Barberis M, Vecchi M. Dama E, et al. Among authors: spaggiari l. Oncotarget. 2016 Jun 14;7(24):37160-37176. doi: 10.18632/oncotarget.9471. Oncotarget. 2016. PMID: 27206799 Free PMC article.
An Aggressive Subtype of Stage I Lung Adenocarcinoma with Molecular and Prognostic Characteristics Typical of Advanced Lung Cancers.
Dama E, Melocchi V, Dezi F, Pirroni S, Carletti RM, Brambilla D, Bertalot G, Casiraghi M, Maisonneuve P, Barberis M, Viale G, Vecchi M, Spaggiari L, Bianchi F, Di Fiore PP. Dama E, et al. Among authors: spaggiari l. Clin Cancer Res. 2017 Jan 1;23(1):62-72. doi: 10.1158/1078-0432.CCR-15-3005. Epub 2016 Jun 29. Clin Cancer Res. 2017. PMID: 27358486
miRNome profiling of lung cancer metastases revealed a key role for miRNA-PD-L1 axis in the modulation of chemotherapy response.
Cuttano R, Colangelo T, Guarize J, Dama E, Cocomazzi MP, Mazzarelli F, Melocchi V, Palumbo O, Marino E, Belloni E, Montani F, Vecchi M, Barberis M, Graziano P, Pasquier A, Sanz-Ortega J, Montuenga LM, Carbonelli C, Spaggiari L, Bianchi F. Cuttano R, et al. Among authors: spaggiari l. J Hematol Oncol. 2022 Dec 31;15(1):178. doi: 10.1186/s13045-022-01394-1. J Hematol Oncol. 2022. PMID: 36587234 Free PMC article.
656 results