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Novel multi-targeting anthra[2,3-b]thiophene-5,10-diones with guanidine-containing side chains: interaction with telomeric G-quadruplex, inhibition of telomerase and topoisomerase I and cytotoxic properties.
Ilyinsky NS, Shchyolkina AK, Borisova OF, Mamaeva OK, Zvereva MI, Azhibek DM, Livshits MA, Mitkevich VA, Balzarini J, Sinkevich YB, Luzikov YN, Dezhenkova LG, Kolotova ES, Shtil AA, Shchekotikhin AE, Kaluzhny DN. Ilyinsky NS, et al. Among authors: borisova of. Eur J Med Chem. 2014 Oct 6;85:605-14. doi: 10.1016/j.ejmech.2014.08.030. Epub 2014 Aug 8. Eur J Med Chem. 2014. PMID: 25127152
Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages.
Varizhuk AM, Tsvetkov VB, Tatarinova ON, Kaluzhny DN, Florentiev VL, Timofeev EN, Shchyolkina AK, Borisova OF, Smirnov IP, Grokhovsky SL, Aseychev AV, Pozmogova GE. Varizhuk AM, et al. Among authors: borisova of. Eur J Med Chem. 2013 Sep;67:90-7. doi: 10.1016/j.ejmech.2013.06.034. Epub 2013 Jun 25. Eur J Med Chem. 2013. PMID: 23850569
Ethidium probing of the parallel double- and four-stranded structures formed by the telomeric DNA sequences dG(GT)4G and d(GT)5.
Beschetnova IA, Kaluzhny DN, Livshits MA, Shchyolkina AK, Borisova OF. Beschetnova IA, et al. Among authors: borisova of. J Biomol Struct Dyn. 2003 Jun;20(6):789-99. doi: 10.1080/07391102.2003.10506895. J Biomol Struct Dyn. 2003. PMID: 12744708
The data conform to the model of Et association with GT-quadruplex suggested earlier [O. F. Borisova et al. ...Thermodynamic parameters of formation of Et:qGT and EtBr:hp-GT complexes were calculated from UV thermal denaturation profiles....
The data conform to the model of Et association with GT-quadruplex suggested earlier [O. F. Borisova et al. ...Thermodynamic p …
Novel antitumor L-arabinose derivative of indolocarbazole with high affinity to DNA.
Kaluzhny DN, Tatarskiy VV Jr, Dezhenkova LG, Plikhtyak IL, Miniker TD, Shchyolkina AK, Strel'tsov SA, Chilov GG, Novikov FN, Kubasova IY, Smirnova ZS, Mel'nik SY, Livshits MA, Borisova OF, Shtil AA. Kaluzhny DN, et al. Among authors: borisova of. ChemMedChem. 2009 Oct;4(10):1641-8. doi: 10.1002/cmdc.200900227. ChemMedChem. 2009. PMID: 19672918
Preferential DNA photocleavage potency of Zn(II) over Ni(II) derivatives of carboxymethyl tetracationic porphyrin: the role of the mode of binding to DNA.
Kovaleva OA, Tsvetkov VB, Mamaeva OK, Ol'shevskaya VA, Makarenkov AV, Dezhenkova LG, Semeikin AS, Borisova OF, Shtil AA, Shchyolkina AK, Kaluzhny DN. Kovaleva OA, et al. Among authors: borisova of. Eur Biophys J. 2014 Nov;43(10-11):545-54. doi: 10.1007/s00249-014-0984-7. Epub 2014 Aug 28. Eur Biophys J. 2014. PMID: 25164439
80 results