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Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule.
Islamov RR, Rizvanov AA, Mukhamedyarov MA, Salafutdinov II, Garanina EE, Fedotova VY, Solovyeva VV, Mukhamedshina YO, Safiullov ZZ, Izmailov AA, Guseva DS, Zefirov AL, Kiyasov AP, Palotas A. Islamov RR, et al. Curr Gene Ther. 2015;15(3):266-76. doi: 10.2174/1566523215666150126122317. Curr Gene Ther. 2015. PMID: 25619885
Genetically modified human umbilical cord blood cells expressing vascular endothelial growth factor and fibroblast growth factor 2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis transgenic mice.
Rizvanov AA, Guseva DS, Salafutdinov II, Kudryashova NV, Bashirov FV, Kiyasov AP, Yalvaç ME, Gazizov IM, Kaligin MS, Sahin F, Mukhamedyarov MA, Palotás A, Islamov RR. Rizvanov AA, et al. Exp Biol Med (Maywood). 2011 Jan;236(1):91-8. doi: 10.1258/ebm.2010.010172. Epub 2010 Dec 16. Exp Biol Med (Maywood). 2011. PMID: 21163822 Free article.
69 results