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Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK.
Hunter RW, Foretz M, Bultot L, Fullerton MD, Deak M, Ross FA, Hawley SA, Shpiro N, Viollet B, Barron D, Kemp BE, Steinberg GR, Hardie DG, Sakamoto K. Hunter RW, et al. Among authors: barron d. Chem Biol. 2014 Jul 17;21(7):866-79. doi: 10.1016/j.chembiol.2014.05.014. Chem Biol. 2014. PMID: 25036776 Free PMC article.
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site.
Sanders MJ, Ratinaud Y, Neopane K, Bonhoure N, Day EA, Ciclet O, Lassueur S, Naranjo Pinta M, Deak M, Brinon B, Christen S, Steinberg GR, Barron D, Sakamoto K. Sanders MJ, et al. Among authors: barron d. J Biol Chem. 2022 May;298(5):101852. doi: 10.1016/j.jbc.2022.101852. Epub 2022 Mar 21. J Biol Chem. 2022. PMID: 35331736 Free PMC article.
First synthesis, characterization, and evidence for the presence of hydroxycinnamic acid sulfate and glucuronide conjugates in human biological fluids as a result of coffee consumption.
Fumeaux R, Menozzi-Smarrito C, Stalmach A, Munari C, Kraehenbuehl K, Steiling H, Crozier A, Williamson G, Barron D. Fumeaux R, et al. Among authors: barron d. Org Biomol Chem. 2010 Nov 21;8(22):5199-211. doi: 10.1039/c0ob00137f. Epub 2010 Sep 14. Org Biomol Chem. 2010. PMID: 20842300 Clinical Trial.
Catechin glucosides: occurrence, synthesis, and stability.
Raab T, Barron D, Vera FA, Crespy V, Oliveira M, Williamson G. Raab T, et al. Among authors: barron d. J Agric Food Chem. 2010 Feb 24;58(4):2138-49. doi: 10.1021/jf9034095. J Agric Food Chem. 2010. PMID: 20112905
695 results