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RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells.
Duewell P, Steger A, Lohr H, Bourhis H, Hoelz H, Kirchleitner SV, Stieg MR, Grassmann S, Kobold S, Siveke JT, Endres S, Schnurr M. Duewell P, et al. Among authors: kirchleitner sv. Cell Death Differ. 2014 Dec;21(12):1825-37. doi: 10.1038/cdd.2014.96. Epub 2014 Jul 11. Cell Death Differ. 2014. PMID: 25012502 Free PMC article.
Correction to: Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.
Metzger P, Kirchleitner SV, Kluge M, Koenig LM, Hörth C, Rambuscheck CA, Böhmer D, Ahlfeld J, Kobold S, Friedel CC, Endres S, Schnurr M, Duewell P. Metzger P, et al. Among authors: kirchleitner sv. J Immunother Cancer. 2019 Dec 16;7(1):349. doi: 10.1186/s40425-019-0830-7. J Immunother Cancer. 2019. PMID: 31843014 Free PMC article.
Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model.
Metzger P, Kirchleitner SV, Boehmer DFR, Hörth C, Eisele A, Ormanns S, Gunzer M, Lech M, Lauber K, Endres S, Duewell P, Schnurr M, König LM. Metzger P, et al. Among authors: kirchleitner sv. Cancer Immunol Immunother. 2020 Oct;69(10):2101-2112. doi: 10.1007/s00262-020-02605-9. Epub 2020 May 24. Cancer Immunol Immunother. 2020. PMID: 32448983 Free PMC article.
TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression.
Kälin RE, Cai L, Li Y, Zhao D, Zhang H, Cheng J, Zhang W, Wu Y, Eisenhut K, Janssen P, Schmitt L, Enard W, Michels F, Flüh C, Hou M, Kirchleitner SV, Siller S, Schiemann M, Andrä I, Montanez E, Giachino C, Taylor V, Synowitz M, Tonn JC, von Baumgarten L, Schulz C, Hellmann I, Glass R. Kälin RE, et al. Among authors: kirchleitner sv. Cell Syst. 2021 Mar 17;12(3):248-262.e7. doi: 10.1016/j.cels.2021.01.002. Epub 2021 Feb 15. Cell Syst. 2021. PMID: 33592194 Free article.
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution.
Bartos LM, Kirchleitner SV, Kolabas ZI, Quach S, Beck A, Lorenz J, Blobner J, Mueller SA, Ulukaya S, Hoeher L, Horvath I, Wind-Mark K, Holzgreve A, Ruf VC, Gold L, Kunze LH, Kunte ST, Beumers P, Park HE, Antons M, Zatcepin A, Briel N, Hoermann L, Schaefer R, Messerer D, Bartenstein P, Riemenschneider MJ, Lindner S, Ziegler S, Herms J, Lichtenthaler SF, Ertürk A, Tonn JC, von Baumgarten L, Albert NL, Brendel M. Bartos LM, et al. Among authors: kirchleitner sv. Sci Adv. 2023 Oct 27;9(43):eadi8986. doi: 10.1126/sciadv.adi8986. Epub 2023 Oct 27. Sci Adv. 2023. PMID: 37889970 Free PMC article.
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