Tekwani BL - Search Results

1

Hydroxylated derivatives of NPC1161: theoretical insights into their potential toxicity and the feasibility and regioselectivity of their formation.

Ding Y, Liu H, Nanayakkara NP, Khan IA, Tekwani BL, Walker LA, Doerksen RJ. Ding Y, et al. Among authors: tekwani bl. J Phys Chem A. 2014 Jul 24;118(29):5501-7. doi: 10.1021/jp502612t. Epub 2014 Jul 11. J Phys Chem A. 2014. PMID: 24956138 Free PMC article.

2

Methemoglobin generation by 8-aminoquinolines: effect of substitution at 5-position of primaquine.

Liu H, Tekwani BL, Nanayakkara NP, Walker LA, Doerksen RJ. Liu H, et al. Among authors: tekwani bl. Chem Res Toxicol. 2013 Dec 16;26(12):1801-9. doi: 10.1021/tx400067a. Epub 2013 Nov 13. Chem Res Toxicol. 2013. PMID: 24224488

3

Methemoglobinemia Hemotoxicity of Some Antimalarial 8-Aminoquinoline Analogues and Their Hydroxylated Derivatives: Density Functional Theory Computation of Ionization Potentials.

Ding Y, Liu H, Tekwani BL, Nanayakkara NP, Khan IA, Walker LA, Doerksen RJ. Ding Y, et al. Among authors: tekwani bl. Chem Res Toxicol. 2016 Jul 18;29(7):1132-41. doi: 10.1021/acs.chemrestox.6b00063. Epub 2016 Jul 1. Chem Res Toxicol. 2016. PMID: 27223244

4

Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.

Tekwani BL, Walker LA. Tekwani BL, et al. Comb Chem High Throughput Screen. 2005 Feb;8(1):63-79. doi: 10.2174/1386207053328101. Comb Chem High Throughput Screen. 2005. PMID: 15720198 Review.

5

8-Aminoquinolines: future role as antiprotozoal drugs.

Tekwani BL, Walker LA. Tekwani BL, et al. Curr Opin Infect Dis. 2006 Dec;19(6):623-31. doi: 10.1097/QCO.0b013e328010b848. Curr Opin Infect Dis. 2006. PMID: 17075340 Review.

6

Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.

Peng J, Kudrimoti S, Prasanna S, Odde S, Doerksen RJ, Pennaka HK, Choo YM, Rao KV, Tekwani BL, Madgula V, Khan SI, Wang B, Mayer AM, Jacob MR, Tu LC, Gertsch J, Hamann MT. Peng J, et al. Among authors: tekwani bl. J Med Chem. 2010 Jan 14;53(1):61-76. doi: 10.1021/jm900672t. J Med Chem. 2010. PMID: 20017491 Free PMC article.

7

Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.

Avula B, Khan SI, Tekwani BL, Nanayakkara NP, McChesney JD, Walker LA, Khan IA. Avula B, et al. Among authors: tekwani bl. Biomed Chromatogr. 2011 Sep;25(9):1010-7. doi: 10.1002/bmc.1557. Epub 2010 Nov 5. Biomed Chromatogr. 2011. PMID: 21058417

8

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

Chaurasiya ND, Ganesan S, Nanayakkara NP, Dias LR, Walker LA, Tekwani BL. Chaurasiya ND, et al. Among authors: tekwani bl. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1701-4. doi: 10.1016/j.bmcl.2011.12.108. Epub 2012 Jan 3. Bioorg Med Chem Lett. 2012. PMID: 22264472

9

Enantioselective metabolism of primaquine by human CYP2D6.

Fasinu PS, Tekwani BL, Nanayakkara NP, Avula B, Herath HM, Wang YH, Adelli VR, Elsohly MA, Khan SI, Khan IA, Pybus BS, Marcsisin SR, Reichard GA, McChesney JD, Walker LA. Fasinu PS, et al. Among authors: tekwani bl. Malar J. 2014 Dec 17;13:507. doi: 10.1186/1475-2875-13-507. Malar J. 2014. PMID: 25518709 Free PMC article.

10

Enantioselective pharmacokinetics of primaquine in healthy human volunteers.

Tekwani BL, Avula B, Sahu R, Chaurasiya ND, Khan SI, Jain S, Fasinu PS, Herath HM, Stanford D, Nanayakkara NP, McChesney JD, Yates TW, ElSohly MA, Khan IA, Walker LA. Tekwani BL, et al. Drug Metab Dispos. 2015 Apr;43(4):571-7. doi: 10.1124/dmd.114.061127. Epub 2015 Jan 30. Drug Metab Dispos. 2015. PMID: 25637634

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