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Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.
Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV. Standaert ML, et al. Among authors: farese rv jr, farese rv. J Biol Chem. 2004 Jun 11;279(24):24929-34. doi: 10.1074/jbc.M402440200. Epub 2004 Apr 6. J Biol Chem. 2004. PMID: 15069067 Free article.
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