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Multi-institutional, randomized, double-blind, placebo-controlled trial to assess the efficacy of a mucoadhesive hydrogel (MuGard) in mitigating oral mucositis symptoms in patients being treated with chemoradiation therapy for cancers of the head and neck.
Allison RR, Ambrad AA, Arshoun Y, Carmel RJ, Ciuba DF, Feldman E, Finkelstein SE, Gandhavadi R, Heron DE, Lane SC, Longo JM, Meakin C, Papadopoulos D, Pruitt DE, Steinbrenner LM, Taylor MA, Wisbeck WM, Yuh GE, Nowotnik DP, Sonis ST. Allison RR, et al. Among authors: sonis st. Cancer. 2014 May 1;120(9):1433-40. doi: 10.1002/cncr.28553. Cancer. 2014. PMID: 24877167 Free PMC article. Clinical Trial.
Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life.
Elting LS, Keefe DM, Sonis ST, Garden AS, Spijkervet FK, Barasch A, Tishler RB, Canty TP, Kudrimoti MK, Vera-Llonch M; Burden of Illness Head and Neck Writing Committee. Elting LS, et al. Among authors: sonis st. Cancer. 2008 Nov 15;113(10):2704-13. doi: 10.1002/cncr.23898. Cancer. 2008. PMID: 18973181 Free article.
Oral mucositis.
Sonis ST. Sonis ST. Anticancer Drugs. 2011 Aug;22(7):607-12. doi: 10.1097/CAD.0b013e3283462086. Anticancer Drugs. 2011. PMID: 21709615 Review.
Phase 1b, multicenter, single blinded, placebo-controlled, sequential dose escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer receiving induction chemotherapy.
Limaye SA, Haddad RI, Cilli F, Sonis ST, Colevas AD, Brennan MT, Hu KS, Murphy BA. Limaye SA, et al. Among authors: sonis st. Cancer. 2013 Dec 15;119(24):4268-76. doi: 10.1002/cncr.28365. Epub 2013 Sep 24. Cancer. 2013. PMID: 24114811 Free article. Clinical Trial.
281 results