Priebe W - Search Results

1

Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo.

Judd LM, Menheniott TR, Ling H, Jackson CB, Howlett M, Kalantzis A, Priebe W, Giraud AS. Judd LM, et al. Among authors: priebe w. PLoS One. 2014 May 7;9(5):e95993. doi: 10.1371/journal.pone.0095993. eCollection 2014. PLoS One. 2014. PMID: 24804649 Free PMC article.

2

Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway.

Sai K, Wang S, Balasubramaniyan V, Conrad C, Lang FF, Aldape K, Szymanski S, Fokt I, Dasgupta A, Madden T, Guan S, Chen Z, Alfred Yung WK, Priebe W, Colman H. Sai K, et al. Among authors: priebe w. J Neurooncol. 2012 May;107(3):487-501. doi: 10.1007/s11060-011-0786-z. Epub 2012 Jan 17. J Neurooncol. 2012. PMID: 22249692

3

Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells.

Lee HT, Xue J, Chou PC, Zhou A, Yang P, Conrad CA, Aldape KD, Priebe W, Patterson C, Sawaya R, Xie K, Huang S. Lee HT, et al. Among authors: priebe w. Oncotarget. 2015 Apr 30;6(12):10016-29. doi: 10.18632/oncotarget.3540. Oncotarget. 2015. PMID: 25881542 Free PMC article.

4

A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo.

Iwamaru A, Szymanski S, Iwado E, Aoki H, Yokoyama T, Fokt I, Hess K, Conrad C, Madden T, Sawaya R, Kondo S, Priebe W, Kondo Y. Iwamaru A, et al. Among authors: priebe w. Oncogene. 2007 Apr 12;26(17):2435-44. doi: 10.1038/sj.onc.1210031. Epub 2006 Oct 16. Oncogene. 2007. PMID: 17043651

5

A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells.

Kong LY, Wei J, Sharma AK, Barr J, Abou-Ghazal MK, Fokt I, Weinberg J, Rao G, Grimm E, Priebe W, Heimberger AB. Kong LY, et al. Among authors: priebe w. Cancer Immunol Immunother. 2009 Jul;58(7):1023-32. doi: 10.1007/s00262-008-0618-y. Epub 2008 Nov 11. Cancer Immunol Immunother. 2009. PMID: 19002459 Free PMC article.

6

Inhibition of p-STAT3 enhances IFN-alpha efficacy against metastatic melanoma in a murine model.

Kong LY, Gelbard A, Wei J, Reina-Ortiz C, Wang Y, Yang EC, Hailemichael Y, Fokt I, Jayakumar A, Qiao W, Fuller GN, Overwijk WW, Priebe W, Heimberger AB. Kong LY, et al. Among authors: priebe w. Clin Cancer Res. 2010 May 1;16(9):2550-61. doi: 10.1158/1078-0432.CCR-10-0279. Epub 2010 Apr 13. Clin Cancer Res. 2010. PMID: 20388845 Free PMC article.

7

The tumor microenvironment expression of p-STAT3 influences the efficacy of cyclophosphamide with WP1066 in murine melanoma models.

Hatiboglu MA, Kong LY, Wei J, Wang Y, McEnery KA, Fuller GN, Qiao W, Davies MA, Priebe W, Heimberger AB. Hatiboglu MA, et al. Among authors: priebe w. Int J Cancer. 2012 Jul 1;131(1):8-17. doi: 10.1002/ijc.26307. Epub 2011 Aug 24. Int J Cancer. 2012. PMID: 21792892 Free PMC article.

8

Hypoxia potentiates glioma-mediated immunosuppression.

Wei J, Wu A, Kong LY, Wang Y, Fuller G, Fokt I, Melillo G, Priebe W, Heimberger AB. Wei J, et al. Among authors: priebe w. PLoS One. 2011 Jan 20;6(1):e16195. doi: 10.1371/journal.pone.0016195. PLoS One. 2011. PMID: 21283755 Free PMC article.

9

Radiation with STAT3 Blockade Triggers Dendritic Cell-T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy.

Ott M, Kassab C, Marisetty A, Hashimoto Y, Wei J, Zamler D, Leu JS, Tomaszowski KH, Sabbagh A, Fang D, Gupta P, Priebe W, Zielinski RJ, Burks JK, Long JP, Kong LY, Fuller GN, DeGroot J, Sulman EP, Heimberger AB. Ott M, et al. Among authors: priebe w. Clin Cancer Res. 2020 Sep 15;26(18):4983-4994. doi: 10.1158/1078-0432.CCR-19-4092. Epub 2020 Jun 30. Clin Cancer Res. 2020. PMID: 32605912 Free PMC article.

10

WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation.

Verstovsek S, Manshouri T, Quintás-Cardama A, Harris D, Cortes J, Giles FJ, Kantarjian H, Priebe W, Estrov Z. Verstovsek S, et al. Among authors: priebe w. Clin Cancer Res. 2008 Feb 1;14(3):788-96. doi: 10.1158/1078-0432.CCR-07-0524. Clin Cancer Res. 2008. PMID: 18245540

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