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Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling.
Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, Green DR, Brodsky IE. Philip NH, et al. Among authors: hu b. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7385-90. doi: 10.1073/pnas.1403252111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799700 Free PMC article.
Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death.
Philip NH, DeLaney A, Peterson LW, Santos-Marrero M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olsen TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, Henao-Mejia J, Brodsky IE. Philip NH, et al. Among authors: hu b. PLoS Pathog. 2016 Oct 13;12(10):e1005910. doi: 10.1371/journal.ppat.1005910. eCollection 2016 Oct. PLoS Pathog. 2016. PMID: 27737018 Free PMC article.
Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.
Wynosky-Dolfi MA, Snyder AG, Philip NH, Doonan PJ, Poffenberger MC, Avizonis D, Zwack EE, Riblett AM, Hu B, Strowig T, Flavell RA, Jones RG, Freedman BD, Brodsky IE. Wynosky-Dolfi MA, et al. Among authors: hu b. J Exp Med. 2014 Apr 7;211(4):653-68. doi: 10.1084/jem.20130627. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638169 Free PMC article.
Assessing the Impact of an Artificial Intelligence-Based Model for Intracranial Aneurysm Detection in CT Angiography on Patient Diagnosis and Outcomes (IDEAL Study)-a protocol for a multicenter, double-blinded randomized controlled trial.
Shi Z, Hu B, Lu M, Chen Z, Zhang M, Yu Y, Zhou C, Zhong J, Wu B, Zhang X, Wei Y, Zhang LJ; China Aneurysm AI Project Group. Shi Z, et al. Among authors: hu b. Trials. 2024 Jun 4;25(1):358. doi: 10.1186/s13063-024-08184-9. Trials. 2024. PMID: 38835091
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