Fitzgerald P - Search Results

1

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling.

Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, Green DR, Brodsky IE. Philip NH, et al. Among authors: fitzgerald l, fitzgerald p. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7385-90. doi: 10.1073/pnas.1403252111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799700 Free PMC article.

2

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

Schuler M, Bossy-Wetzel E, Goldstein JC, Fitzgerald P, Green DR. Schuler M, et al. Among authors: fitzgerald p. J Biol Chem. 2000 Mar 10;275(10):7337-42. doi: 10.1074/jbc.275.10.7337. J Biol Chem. 2000. PMID: 10702305 Free article.

3

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain.

Ricci JE, Muñoz-Pinedo C, Fitzgerald P, Bailly-Maitre B, Perkins GA, Yadava N, Scheffler IE, Ellisman MH, Green DR. Ricci JE, et al. Among authors: fitzgerald p. Cell. 2004 Jun 11;117(6):773-86. doi: 10.1016/j.cell.2004.05.008. Cell. 2004. PMID: 15186778 Free article.

4

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.

Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, Droin N, Ulevitch RJ, Green DR, Nicholson DW. Saleh M, et al. Among authors: fitzgerald p. Nature. 2006 Apr 20;440(7087):1064-8. doi: 10.1038/nature04656. Nature. 2006. PMID: 16625199

5

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.

Muñoz-Pinedo C, Guío-Carrión A, Goldstein JC, Fitzgerald P, Newmeyer DD, Green DR. Muñoz-Pinedo C, et al. Among authors: fitzgerald p. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11573-8. doi: 10.1073/pnas.0603007103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864784 Free PMC article.

6

Role of proteolysis in caspase-8 activation and stabilization.

Pop C, Fitzgerald P, Green DR, Salvesen GS. Pop C, et al. Among authors: fitzgerald p. Biochemistry. 2007 Apr 10;46(14):4398-407. doi: 10.1021/bi602623b. Epub 2007 Mar 20. Biochemistry. 2007. PMID: 17371051

7

Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.

Ayrault O, Godeny MD, Dillon C, Zindy F, Fitzgerald P, Roussel MF, Beere HM. Ayrault O, et al. Among authors: fitzgerald p. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17037-42. doi: 10.1073/pnas.0902880106. Epub 2009 Sep 23. Proc Natl Acad Sci U S A. 2009. PMID: 19805107 Free PMC article.

8

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.

Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C, Hakem R, Salvesen GS, Green DR. Oberst A, et al. Among authors: fitzgerald p. Nature. 2011 Mar 17;471(7338):363-7. doi: 10.1038/nature09852. Epub 2011 Mar 2. Nature. 2011. PMID: 21368763 Free PMC article.

9

Non-apoptotic role of BID in inflammation and innate immunity.

Yeretssian G, Correa RG, Doiron K, Fitzgerald P, Dillon CP, Green DR, Reed JC, Saleh M. Yeretssian G, et al. Among authors: fitzgerald p. Nature. 2011 Jun 2;474(7349):96-9. doi: 10.1038/nature09982. Epub 2011 May 8. Nature. 2011. PMID: 21552281

10

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells.

Martinez J, Almendinger J, Oberst A, Ness R, Dillon CP, Fitzgerald P, Hengartner MO, Green DR. Martinez J, et al. Among authors: fitzgerald p. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17396-401. doi: 10.1073/pnas.1113421108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969579 Free PMC article.

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