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von Willebrand factor directly interacts with DNA from neutrophil extracellular traps.
Grässle S, Huck V, Pappelbaum KI, Gorzelanny C, Aponte-Santamaría C, Baldauf C, Gräter F, Schneppenheim R, Obser T, Schneider SW. Grässle S, et al. Among authors: obser t. Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1382-9. doi: 10.1161/ATVBAHA.113.303016. Epub 2014 May 1. Arterioscler Thromb Vasc Biol. 2014. PMID: 24790143
Ultralarge von Willebrand factor fibers mediate luminal Staphylococcus aureus adhesion to an intact endothelial cell layer under shear stress.
Pappelbaum KI, Gorzelanny C, Grässle S, Suckau J, Laschke MW, Bischoff M, Bauer C, Schorpp-Kistner M, Weidenmaier C, Schneppenheim R, Obser T, Sinha B, Schneider SW. Pappelbaum KI, et al. Among authors: obser t. Circulation. 2013 Jul 2;128(1):50-9. doi: 10.1161/CIRCULATIONAHA.113.002008. Epub 2013 May 29. Circulation. 2013. PMID: 23720451
von Willebrand factor is dimerized by protein disulfide isomerase.
Lippok S, Kolšek K, Löf A, Eggert D, Vanderlinden W, Müller JP, König G, Obser T, Röhrs K, Schneppenheim S, Budde U, Baldauf C, Aponte-Santamaría C, Gräter F, Schneppenheim R, Rädler JO, Brehm MA. Lippok S, et al. Among authors: obser t. Blood. 2016 Mar 3;127(9):1183-91. doi: 10.1182/blood-2015-04-641902. Epub 2015 Dec 15. Blood. 2016. PMID: 26670633 Free article.
Mutual A domain interactions in the force sensing protein von Willebrand factor.
Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm MA, Gruber HJ, Netz RR, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P. Posch S, et al. Among authors: obser t. J Struct Biol. 2017 Jan;197(1):57-64. doi: 10.1016/j.jsb.2016.04.012. Epub 2016 Apr 23. J Struct Biol. 2017. PMID: 27113902 Free article.
Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy.
Nicolay JP, Thorn V, Daniel C, Amann K, Siraskar B, Lang F, Hillgruber C, Goerge T, Hoffmann S, Gorzelanny C, Huck V, Mess C, Obser T, Schneppenheim R, Fleming I, Schneider MF, Schneider SW. Nicolay JP, et al. Among authors: obser t. Sci Rep. 2018 Jul 19;8(1):10945. doi: 10.1038/s41598-018-28961-2. Sci Rep. 2018. PMID: 30026593 Free PMC article.
Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor.
Xu ER, von Bülow S, Chen PC, Lenting PJ, Kolšek K, Aponte-Santamaría C, Simon B, Foot J, Obser T, Schneppenheim R, Gräter F, Denis CV, Wilmanns M, Hennig J. Xu ER, et al. Among authors: obser t. Blood. 2019 Jan 24;133(4):366-376. doi: 10.1182/blood-2018-04-843615. Epub 2018 Oct 10. Blood. 2019. PMID: 30305279 Free PMC article.
Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics.
Huck V, Chen PC, Xu ER, Tischer A, Klemm U, Aponte-Santamaría C, Mess C, Obser T, Kutzki F, König G, Denis CV, Gräter F, Wilmanns M, Auton M, Schneider SW, Schneppenheim R, Hennig J, Brehm MA. Huck V, et al. Among authors: obser t. Thromb Haemost. 2022 Feb;122(2):226-239. doi: 10.1055/a-1344-4405. Epub 2021 Apr 14. Thromb Haemost. 2022. PMID: 33385180 Free PMC article.
63 results