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Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.
Trenholme K, Marek L, Duffy S, Pradel G, Fisher G, Hansen FK, Skinner-Adams TS, Butterworth A, Ngwa CJ, Moecking J, Goodman CD, McFadden GI, Sumanadasa SD, Fairlie DP, Avery VM, Kurz T, Andrews KT. Trenholme K, et al. Among authors: butterworth a. Antimicrob Agents Chemother. 2014 Jul;58(7):3666-78. doi: 10.1128/AAC.02721-13. Epub 2014 Apr 14. Antimicrob Agents Chemother. 2014. PMID: 24733477 Free PMC article.
Plasmodium falciparum gametocytes: with a view to a kill.
Butterworth AS, Skinner-Adams TS, Gardiner DL, Trenholme KR. Butterworth AS, et al. Parasitology. 2013 Dec;140(14):1718-34. doi: 10.1017/S0031182013001236. Epub 2013 Aug 19. Parasitology. 2013. PMID: 23953486 Review.
The development of sexual stage malaria gametocytes in a Wave Bioreactor.
Demanga CG, Eng JWL, Gardiner DL, Roth A, Butterworth A, Adams JH, Trenholme KR, Dalton JP. Demanga CG, et al. Among authors: butterworth a. Parasit Vectors. 2017 May 2;10(1):216. doi: 10.1186/s13071-017-2155-z. Parasit Vectors. 2017. PMID: 28464929 Free PMC article.
The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment.
Skinner-Adams TS, Butterworth AS, Porter KA, D'Amico R, Sawe F, Shaffer D, Siika A, Hosseinipour MC, Stringer E, Currier JS, Chipato T, Salata R, Lockman S, Eron JJ, Meshnick SR, McCarthy JS. Skinner-Adams TS, et al. Among authors: butterworth as. PLoS One. 2012;7(4):e34399. doi: 10.1371/journal.pone.0034399. Epub 2012 Apr 3. PLoS One. 2012. PMID: 22509297 Free PMC article. Clinical Trial.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, De Borst MH, Polašek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poulter N, … See abstract for full author list ➔ Keaton JM, et al. Among authors: butterworth as. Nat Genet. 2024 May;56(5):778-791. doi: 10.1038/s41588-024-01714-w. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689001 Free PMC article.
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
Smith-Byrne K, Hedman Å, Dimitriou M, Desai T, Sokolov AV, Schioth HB, Koprulu M, Pietzner M, Langenberg C, Atkins J, Penha RC, McKay J, Brennan P, Zhou S, Richards BJ, Yarmolinsky J, Martin RM, Borlido J, Mu XJ, Butterworth A, Shen X, Wilson J, Assimes TL, Hung RJ, Amos C, Purdue M, Rothman N, Chanock S, Travis RC, Johansson M, Mälarstig A. Smith-Byrne K, et al. Among authors: butterworth a. Nat Commun. 2024 Apr 29;15(1):3621. doi: 10.1038/s41467-024-46834-3. Nat Commun. 2024. PMID: 38684708 Free PMC article.
587 results