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A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers.
Okour M, Derimanov G, Barnett R, Fernandez E, Ferrer S, Gresham S, Hossain M, Gamo FJ, Koh G, Pereira A, Rolfe K, Wong D, Young G, Rami H, Haselden J. Okour M, et al. Br J Clin Pharmacol. 2018 Mar;84(3):482-489. doi: 10.1111/bcp.13476. Epub 2017 Dec 29. Br J Clin Pharmacol. 2018. PMID: 29168205 Free PMC article. Clinical Trial.
Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability Determination.
Mahar KM, Caltabiano S, Andrews S, Ramanjineyulu B, Chen L, Young G, Pereira A, Lindsay AC, van den Berg F, Cobitz AR. Mahar KM, et al. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1419-1431. doi: 10.1002/cpdd.1029. Epub 2021 Oct 28. Clin Pharmacol Drug Dev. 2021. PMID: 34713596 Free PMC article.
Pharmacokinetics, Excretion, and Mass Balance of [14 C]-Batefenterol Following a Single Microtracer Intravenous Dose (Concomitant to an Inhaled Dose) or Oral Dose of Batefenterol in Healthy Men.
Ambery C, Young G, Fuller T, Lazaar AL, Pereira A, Hughes A, Ramsay D, van den Berg F, Daley-Yates P. Ambery C, et al. Clin Pharmacol Drug Dev. 2018 Nov;7(8):901-910. doi: 10.1002/cpdd.616. Epub 2018 Sep 19. Clin Pharmacol Drug Dev. 2018. PMID: 30230263 Free PMC article. Clinical Trial.
An Innovative Approach to Characterize Clinical ADME and Pharmacokinetics of the Inhaled Drug Nemiralisib Using an Intravenous Microtracer Combined with an Inhaled Dose and an Oral Radiolabel Dose in Healthy Male Subjects.
Harrell AW, Wilson R, Man YL, Riddell K, Jarvis E, Young G, Chambers R, Crossman L, Georgiou A, Pereira A, Kenworthy D, Beaumont C, Marotti M, Wilkes D, Hessel EM, Fahy WA. Harrell AW, et al. Drug Metab Dispos. 2019 Dec;47(12):1457-1468. doi: 10.1124/dmd.119.088344. Epub 2019 Oct 24. Drug Metab Dispos. 2019. PMID: 31649125 Clinical Trial.
Pharmacokinetics and ADME Characterization of Intravenous and Oral [14C]-Linerixibat in Healthy Male Volunteers.
Zamek-Gliszczynski MJ, Kenworthy D, Bershas DA, Sanghvi M, Pereira AI, Mudunuru J, Crossman L, Pirhalla JL, Thorpe KM, Dennison JMTJ, McLaughlin MM, Allinder M, Swift B, O'Connor-Semmes RL, Young GC. Zamek-Gliszczynski MJ, et al. Among authors: young gc. Drug Metab Dispos. 2021 Dec;49(12):1109-1117. doi: 10.1124/dmd.121.000595. Epub 2021 Oct 8. Drug Metab Dispos. 2021. PMID: 34625435 Clinical Trial.
A Novel Method for Studying the Pharmacokinetics of [(14) C]Umeclidinium After Application to the Axilla or Palm of Healthy Male Subjects.
Pene Dumitrescu T, Santos LL, Hughes SC, Pereira AI, Young GC, Hussey E, Charlton P, Baptiste-Brown S, Stuart JS, Vincent V, van Marle SP, Schmith VD. Pene Dumitrescu T, et al. Among authors: young gc. Clin Transl Sci. 2016 Aug;9(4):183-91. doi: 10.1111/cts.12406. Epub 2016 Jun 15. Clin Transl Sci. 2016. PMID: 27304394 Free PMC article. Clinical Trial.
75 results