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PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer.
Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, Knudsen KE, Kitabayashi N, Rubin MA, Demichelis F, Lawrence TS, Chinnaiyan AM, Feng FY. Prensner JR, et al. Among authors: han s. Cancer Res. 2014 Mar 15;74(6):1651-60. doi: 10.1158/0008-5472.CAN-13-3159. Epub 2014 Jan 28. Cancer Res. 2014. PMID: 24473064 Free PMC article.
PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma.
Brenner JC, Feng FY, Han S, Patel S, Goyal SV, Bou-Maroun LM, Liu M, Lonigro R, Prensner JR, Tomlins SA, Chinnaiyan AM. Brenner JC, et al. Among authors: han s. Cancer Res. 2012 Apr 1;72(7):1608-13. doi: 10.1158/0008-5472.CAN-11-3648. Epub 2012 Jan 27. Cancer Res. 2012. PMID: 22287547 Free PMC article.
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex.
Prensner JR, Iyer MK, Sahu A, Asangani IA, Cao Q, Patel L, Vergara IA, Davicioni E, Erho N, Ghadessi M, Jenkins RB, Triche TJ, Malik R, Bedenis R, McGregor N, Ma T, Chen W, Han S, Jing X, Cao X, Wang X, Chandler B, Yan W, Siddiqui J, Kunju LP, Dhanasekaran SM, Pienta KJ, Feng FY, Chinnaiyan AM. Prensner JR, et al. Among authors: han s. Nat Genet. 2013 Nov;45(11):1392-8. doi: 10.1038/ng.2771. Epub 2013 Sep 29. Nat Genet. 2013. PMID: 24076601 Free PMC article.
The lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer.
Malik R, Patel L, Prensner JR, Shi Y, Iyer MK, Subramaniyan S, Carley A, Niknafs YS, Sahu A, Han S, Ma T, Liu M, Asangani IA, Jing X, Cao X, Dhanasekaran SM, Robinson DR, Feng FY, Chinnaiyan AM. Malik R, et al. Among authors: han s. Mol Cancer Res. 2014 Aug;12(8):1081-7. doi: 10.1158/1541-7786.MCR-14-0257. Epub 2014 Jul 16. Mol Cancer Res. 2014. PMID: 25030374 Free PMC article.
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc.
Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Kothari V, Evans JR, Knudsen KE, Paulsen MT, Ljungman M, Lawrence TS, Chinnaiyan AM, Feng FY. Prensner JR, et al. Among authors: han s. Neoplasia. 2014 Nov 20;16(11):900-8. doi: 10.1016/j.neo.2014.09.001. eCollection 2014 Nov. Neoplasia. 2014. PMID: 25425964 Free PMC article.
Dual roles of PARP-1 promote cancer growth and progression.
Schiewer MJ, Goodwin JF, Han S, Brenner JC, Augello MA, Dean JL, Liu F, Planck JL, Ravindranathan P, Chinnaiyan AM, McCue P, Gomella LG, Raj GV, Dicker AP, Brody JR, Pascal JM, Centenera MM, Butler LM, Tilley WD, Feng FY, Knudsen KE. Schiewer MJ, et al. Among authors: han s. Cancer Discov. 2012 Dec;2(12):1134-49. doi: 10.1158/2159-8290.CD-12-0120. Epub 2012 Sep 19. Cancer Discov. 2012. PMID: 22993403 Free PMC article.
A hormone-DNA repair circuit governs the response to genotoxic insult.
Goodwin JF, Schiewer MJ, Dean JL, Schrecengost RS, de Leeuw R, Han S, Ma T, Den RB, Dicker AP, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: han s. Cancer Discov. 2013 Nov;3(11):1254-71. doi: 10.1158/2159-8290.CD-13-0108. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027197 Free PMC article.
The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression.
Niknafs YS, Han S, Ma T, Speers C, Zhang C, Wilder-Romans K, Iyer MK, Pitchiaya S, Malik R, Hosono Y, Prensner JR, Poliakov A, Singhal U, Xiao L, Kregel S, Siebenaler RF, Zhao SG, Uhl M, Gawronski A, Hayes DF, Pierce LJ, Cao X, Collins C, Backofen R, Sahinalp CS, Rae JM, Chinnaiyan AM, Feng FY. Niknafs YS, et al. Among authors: han s. Nat Commun. 2016 Sep 26;7:12791. doi: 10.1038/ncomms12791. Nat Commun. 2016. PMID: 27666543 Free PMC article.
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