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Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Ataide MA, et al. Among authors: golenbock dt. PLoS Pathog. 2014 Jan;10(1):e1003885. doi: 10.1371/journal.ppat.1003885. Epub 2014 Jan 16. PLoS Pathog. 2014. PMID: 24453977 Free PMC article. Clinical Trial.
The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria.
Antonelli LR, Leoratti FM, Costa PA, Rocha BC, Diniz SQ, Tada MS, Pereira DB, Teixeira-Carvalho A, Golenbock DT, Gonçalves R, Gazzinelli RT. Antonelli LR, et al. Among authors: golenbock dt. PLoS Pathog. 2014 Sep 18;10(9):e1004393. doi: 10.1371/journal.ppat.1004393. eCollection 2014 Sep. PLoS Pathog. 2014. PMID: 25233271 Free PMC article.
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.
Hirako IC, Gallego-Marin C, Ataide MA, Andrade WA, Gravina H, Rocha BC, de Oliveira RB, Pereira DB, Vinetz J, Diamond B, Ram S, Golenbock DT, Gazzinelli RT. Hirako IC, et al. Among authors: golenbock dt. mBio. 2015 Nov 17;6(6):e01605-15. doi: 10.1128/mBio.01605-15. mBio. 2015. PMID: 26578679 Free PMC article.
Caspase-8 mediates inflammation and disease in rodent malaria.
Pereira LMN, Assis PA, de Araújo NM, Durso DF, Junqueira C, Ataíde MA, Pereira DB, Lien E, Fitzgerald KA, Zamboni DS, Golenbock DT, Gazzinelli RT. Pereira LMN, et al. Among authors: golenbock dt. Nat Commun. 2020 Sep 14;11(1):4596. doi: 10.1038/s41467-020-18295-x. Nat Commun. 2020. PMID: 32929083 Free PMC article.
Neutrophil paralysis in Plasmodium vivax malaria.
Leoratti FM, Trevelin SC, Cunha FQ, Rocha BC, Costa PA, Gravina HD, Tada MS, Pereira DB, Golenbock DT, Antonelli LR, Gazzinelli RT. Leoratti FM, et al. Among authors: golenbock dt. PLoS Negl Trop Dis. 2012;6(6):e1710. doi: 10.1371/journal.pntd.0001710. Epub 2012 Jun 26. PLoS Negl Trop Dis. 2012. PMID: 22745844 Free PMC article.
MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.
Franklin BS, Rodrigues SO, Antonelli LR, Oliveira RV, Goncalves AM, Sales-Junior PA, Valente EP, Alvarez-Leite JI, Ropert C, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Among authors: golenbock dt. Microbes Infect. 2007 Jun;9(7):881-90. doi: 10.1016/j.micinf.2007.03.007. Epub 2007 Mar 21. Microbes Infect. 2007. PMID: 17537666 Free article.
Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.
Franklin BS, Parroche P, Ataíde MA, Lauw F, Ropert C, de Oliveira RB, Pereira D, Tada MS, Nogueira P, da Silva LH, Bjorkbacka H, Golenbock DT, Gazzinelli RT. Franklin BS, et al. Among authors: golenbock dt. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5789-94. doi: 10.1073/pnas.0809742106. Epub 2009 Mar 18. Proc Natl Acad Sci U S A. 2009. PMID: 19297619 Free PMC article.
256 results