Kirkby NS - Search Results

1

Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay.

Lordkipanidzé M, Lowe GC, Kirkby NS, Chan MV, Lundberg MH, Morgan NV, Bem D, Nisar SP, Leo VC, Jones ML, Mundell SJ, Daly ME, Mumford AD, Warner TD, Watson SP; UK Genotyping and Phenotyping of Platelets Study Group. Lordkipanidzé M, et al. Among authors: kirkby ns. Blood. 2014 Feb 20;123(8):e11-22. doi: 10.1182/blood-2013-08-520387. Epub 2014 Jan 9. Blood. 2014. PMID: 24408324 Free PMC article.

2

In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.

Armstrong PC, Leadbeater PD, Chan MV, Kirkby NS, Jakubowski JA, Mitchell JA, Warner TD. Armstrong PC, et al. Among authors: kirkby ns. J Thromb Haemost. 2011 Mar;9(3):552-61. doi: 10.1111/j.1538-7836.2010.04160.x. J Thromb Haemost. 2011. PMID: 21143373 Free PMC article.

3

Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.

Armstrong PC, Kirkby NS, Zain ZN, Emerson M, Mitchell JA, Warner TD. Armstrong PC, et al. Among authors: kirkby ns. PLoS One. 2011;6(5):e20062. doi: 10.1371/journal.pone.0020062. Epub 2011 May 23. PLoS One. 2011. PMID: 21629780 Free PMC article.

4

Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel.

Leadbeater PD, Kirkby NS, Thomas S, Dhanji AR, Tucker AT, Milne GL, Mitchell JA, Warner TD. Leadbeater PD, et al. Among authors: kirkby ns. J Thromb Haemost. 2011 Oct;9(10):2050-6. doi: 10.1111/j.1538-7836.2011.04450.x. J Thromb Haemost. 2011. PMID: 21794076 Free PMC article.

5

Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing.

Chan MV, Armstrong PC, Papalia F, Kirkby NS, Warner TD. Chan MV, et al. Among authors: kirkby ns. Platelets. 2011;22(7):485-94. doi: 10.3109/09537104.2011.592958. Epub 2011 Aug 2. Platelets. 2011. PMID: 21806492

6

Antiplatelet effects of aspirin vary with level of P2Y₁₂ receptor blockade supplied by either ticagrelor or prasugrel.

Kirkby NS, Leadbeater PD, Chan MV, Nylander S, Mitchell JA, Warner TD. Kirkby NS, et al. J Thromb Haemost. 2011 Oct;9(10):2103-5. doi: 10.1111/j.1538-7836.2011.04453.x. J Thromb Haemost. 2011. PMID: 21812912 Free PMC article. No abstract available.

7

Short thromboelastography and the identification of high platelet reactivity while on and off therapy.

Warner TD, Mitchell JA, Kirkby NS. Warner TD, et al. Among authors: kirkby ns. Heart. 2012 May;98(9):679-80. doi: 10.1136/heartjnl-2012-301676. Heart. 2012. PMID: 22523052 No abstract available.

8

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system.

Kirkby NS, Lundberg MH, Harrington LS, Leadbeater PD, Milne GL, Potter CM, Al-Yamani M, Adeyemi O, Warner TD, Mitchell JA. Kirkby NS, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17597-602. doi: 10.1073/pnas.1209192109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045674 Free PMC article.

9

Circulating microRNAs as novel biomarkers for platelet activation.

Willeit P, Zampetaki A, Dudek K, Kaudewitz D, King A, Kirkby NS, Crosby-Nwaobi R, Prokopi M, Drozdov I, Langley SR, Sivaprasad S, Markus HS, Mitchell JA, Warner TD, Kiechl S, Mayr M. Willeit P, et al. Among authors: kirkby ns. Circ Res. 2013 Feb 15;112(4):595-600. doi: 10.1161/CIRCRESAHA.111.300539. Epub 2013 Jan 2. Circ Res. 2013. PMID: 23283721

10

Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test.

Kirkby NS, Chan MV, Lundberg MH, Massey KA, Edmands WM, MacKenzie LS, Holmes E, Nicolaou A, Warner TD, Mitchell JA. Kirkby NS, et al. FASEB J. 2013 Oct;27(10):3938-46. doi: 10.1096/fj.12-215533. Epub 2013 Jun 21. FASEB J. 2013. PMID: 23792301 Free PMC article.

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