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TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of BUB1B as causative of PCS (MVA) syndrome.
Ochiai H, Miyamoto T, Kanai A, Hosoba K, Sakuma T, Kudo Y, Asami K, Ogawa A, Watanabe A, Kajii T, Yamamoto T, Matsuura S. Ochiai H, et al. Among authors: kanai a. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1461-6. doi: 10.1073/pnas.1317008111. Epub 2013 Dec 16. Proc Natl Acad Sci U S A. 2014. PMID: 24344301 Free PMC article.
Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.
Ueda T, Nakata Y, Nagamachi A, Yamasaki N, Kanai A, Sera Y, Sasaki M, Matsui H, Honda Z, Oda H, Wolff L, Inaba T, Honda H. Ueda T, et al. Among authors: kanai a. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):10370-5. doi: 10.1073/pnas.1600070113. Epub 2016 Aug 30. Proc Natl Acad Sci U S A. 2016. PMID: 27578866 Free PMC article.
Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H. Nakata Y, et al. Among authors: kanai a. Blood. 2017 Apr 13;129(15):2148-2160. doi: 10.1182/blood-2016-06-724658. Epub 2017 Feb 16. Blood. 2017. PMID: 28209720 Free PMC article.
Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type.
Nishimura A, Yokoyama K, Naruto T, Yamagishi C, Imamura T, Nakazono H, Kimura S, Ito M, Sagisaka M, Tanaka Y, Piao J, Namikawa Y, Yanagimachi M, Isoda T, Kanai A, Matsui H, Isobe T, Sato-Otsubo A, Higuchi N, Takada A, Okuno H, Saito S, Karakawa S, Kobayashi S, Hasegawa D, Fujisaki H, Hasegawa D, Koike K, Koike T, Rai S, Umeda K, Sano H, Sekinaka Y, Ogawa A, Kinoshita A, Shiba N, Miki M, Kimura F, Nakayama H, Nakazawa Y, Taga T, Taki T, Adachi S, Manabe A, Koh K, Ishida Y, Takita J, Ishikawa F, Goto H, Morio T, Mizutani S, Tojo A, Takagi M. Nishimura A, et al. Among authors: kanai a. Sci Adv. 2023 Dec 15;9(50):eadj4407. doi: 10.1126/sciadv.adj4407. Epub 2023 Dec 13. Sci Adv. 2023. PMID: 38091391 Free PMC article.
Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia.
Kadono M, Kanai A, Nagamachi A, Shinriki S, Kawata J, Iwato K, Kyo T, Oshima K, Yokoyama A, Kawamura T, Nagase R, Inoue D, Kitamura T, Inaba T, Ichinohe T, Matsui H. Kadono M, et al. Among authors: kanai a. Exp Hematol. 2016 Aug;44(8):745-754.e4. doi: 10.1016/j.exphem.2016.04.017. Epub 2016 May 9. Exp Hematol. 2016. PMID: 27174803 Free article.
Rapid emergence of telaprevir resistant hepatitis C virus strain from wildtype clone in vivo.
Hiraga N, Imamura M, Abe H, Hayes CN, Kono T, Onishi M, Tsuge M, Takahashi S, Ochi H, Iwao E, Kamiya N, Yamada I, Tateno C, Yoshizato K, Matsui H, Kanai A, Inaba T, Tanaka S, Chayama K. Hiraga N, et al. Among authors: kanai a. Hepatology. 2011 Sep 2;54(3):781-8. doi: 10.1002/hep.24460. Epub 2011 Aug 2. Hepatology. 2011. PMID: 21626527
628 results