Pedicord DL - Search Results

1

Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity.

Appiah KK, Blat Y, Robertson BJ, Pearce BC, Pedicord DL, Gentles RG, Yu XC, Mseeh F, Nguyen N, Swaffield JC, Harden DG, Westphal RS, Banks MN, O'Connell JC. Appiah KK, et al. Among authors: pedicord dl. J Biomol Screen. 2014 Apr;19(4):595-605. doi: 10.1177/1087057113511111. Epub 2013 Nov 15. J Biomol Screen. 2014. PMID: 24241710

2

Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α.

Pedicord DL, Flynn MJ, Fanslau C, Miranda M, Hunihan L, Robertson BJ, Pearce BC, Yu XC, Westphal RS, Blat Y. Pedicord DL, et al. Biochem Biophys Res Commun. 2011 Aug 12;411(4):809-14. doi: 10.1016/j.bbrc.2011.07.037. Epub 2011 Jul 20. Biochem Biophys Res Commun. 2011. PMID: 21787747

3

A general liquid chromatography/mass spectroscopy-based assay for detection and quantitation of methyltransferase activity.

Salyan ME, Pedicord DL, Bergeron L, Mintier GA, Hunihan L, Kuit K, Balanda LA, Robertson BJ, Feder JN, Westphal R, Shipkova PA, Blat Y. Salyan ME, et al. Among authors: pedicord dl. Anal Biochem. 2006 Feb 1;349(1):112-7. doi: 10.1016/j.ab.2005.10.040. Epub 2005 Nov 17. Anal Biochem. 2006. PMID: 16325755

4

Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex.

Yoshino H, Miyamae T, Hansen G, Zambrowicz B, Flynn M, Pedicord D, Blat Y, Westphal RS, Zaczek R, Lewis DA, Gonzalez-Burgos G. Yoshino H, et al. J Physiol. 2011 Oct 15;589(Pt 20):4857-84. doi: 10.1113/jphysiol.2011.212225. Epub 2011 Aug 1. J Physiol. 2011. PMID: 21807615 Free PMC article.

5

Substrate-dependent modulation of the mechanism of factor XIa inhibition.

Pedicord DL, Seiffert D, Blat Y. Pedicord DL, et al. Biochemistry. 2004 Sep 21;43(37):11883-8. doi: 10.1021/bi048964g. Biochemistry. 2004. PMID: 15362874

6

Feedback activation of factor XI by thrombin does not occur in plasma.

Pedicord DL, Seiffert D, Blat Y. Pedicord DL, et al. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12855-60. doi: 10.1073/pnas.0705566104. Epub 2007 Jul 25. Proc Natl Acad Sci U S A. 2007. PMID: 17652512 Free PMC article.

7

An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors.

Fanslau C, Pedicord D, Nagulapalli S, Gray H, Pang S, Jayaraman L, Lippy J, Blat Y. Fanslau C, et al. Anal Biochem. 2010 Jul 1;402(1):65-8. doi: 10.1016/j.ab.2010.03.025. Epub 2010 Mar 23. Anal Biochem. 2010. PMID: 20338149

8

Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency.

Sahni-Arya B, Flynn MJ, Bergeron L, Salyan ME, Pedicord DL, Golla R, Ma Z, Wang H, Seethala R, Wu SC, Li JJ, Nayeem A, Gates C, Hamann LG, Gordon DA, Blat Y. Sahni-Arya B, et al. Among authors: pedicord dl. Biochim Biophys Acta. 2007 Sep;1774(9):1184-91. doi: 10.1016/j.bbapap.2007.07.005. Epub 2007 Jul 19. Biochim Biophys Acta. 2007. PMID: 17707701

9

Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2.

Purandare AV, McDevitt TM, Wan H, You D, Penhallow B, Han X, Vuppugalla R, Zhang Y, Ruepp SU, Trainor GL, Lombardo L, Pedicord D, Gottardis MM, Ross-Macdonald P, de Silva H, Hosbach J, Emanuel SL, Blat Y, Fitzpatrick E, Taylor TL, McIntyre KW, Michaud E, Mulligan C, Lee FY, Woolfson A, Lasho TL, Pardanani A, Tefferi A, Lorenzi MV. Purandare AV, et al. Leukemia. 2012 Feb;26(2):280-8. doi: 10.1038/leu.2011.292. Epub 2011 Oct 21. Leukemia. 2012. PMID: 22015772

10

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.

Tokarski JS, Zupa-Fernandez A, Tredup JA, Pike K, Chang C, Xie D, Cheng L, Pedicord D, Muckelbauer J, Johnson SR, Wu S, Edavettal SC, Hong Y, Witmer MR, Elkin LL, Blat Y, Pitts WJ, Weinstein DS, Burke JR. Tokarski JS, et al. J Biol Chem. 2015 Apr 24;290(17):11061-74. doi: 10.1074/jbc.M114.619502. Epub 2015 Mar 11. J Biol Chem. 2015. PMID: 25762719 Free PMC article.

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