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A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.
De Muylder G, Daulouède S, Lecordier L, Uzureau P, Morias Y, Van Den Abbeele J, Caljon G, Hérin M, Holzmuller P, Semballa S, Courtois P, Vanhamme L, Stijlemans B, De Baetselier P, Barrett MP, Barlow JL, McKenzie AN, Barron L, Wynn TA, Beschin A, Vincendeau P, Pays E. De Muylder G, et al. Among authors: de baetselier p. PLoS Pathog. 2013 Oct;9(10):e1003731. doi: 10.1371/journal.ppat.1003731. Epub 2013 Oct 31. PLoS Pathog. 2013. PMID: 24204274 Free PMC article.
Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host.
Salmon D, Vanwalleghem G, Morias Y, Denoeud J, Krumbholz C, Lhommé F, Bachmaier S, Kador M, Gossmann J, Dias FB, De Muylder G, Uzureau P, Magez S, Moser M, De Baetselier P, Van Den Abbeele J, Beschin A, Boshart M, Pays E. Salmon D, et al. Among authors: de baetselier p, de muylder g. Science. 2012 Jul 27;337(6093):463-6. doi: 10.1126/science.1222753. Epub 2012 Jun 14. Science. 2012. PMID: 22700656
African trypanosome control in the insect vector and mammalian host.
Beschin A, Van Den Abbeele J, De Baetselier P, Pays E. Beschin A, et al. Among authors: de baetselier p. Trends Parasitol. 2014 Nov;30(11):538-47. doi: 10.1016/j.pt.2014.08.006. Epub 2014 Sep 19. Trends Parasitol. 2014. PMID: 25246021 Review.
High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.
Stijlemans B, Caljon G, Natesan SK, Saerens D, Conrath K, Pérez-Morga D, Skepper JN, Nikolaou A, Brys L, Pays E, Magez S, Field MC, De Baetselier P, Muyldermans S. Stijlemans B, et al. Among authors: de baetselier p. PLoS Pathog. 2011 Jun;7(6):e1002072. doi: 10.1371/journal.ppat.1002072. Epub 2011 Jun 16. PLoS Pathog. 2011. PMID: 21698216 Free PMC article.
IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice.
Bosschaerts T, Morias Y, Stijlemans B, Hérin M, Porta C, Sica A, Mantovani A, De Baetselier P, Beschin A. Bosschaerts T, et al. Among authors: de baetselier p. Eur J Immunol. 2011 Nov;41(11):3270-80. doi: 10.1002/eji.201041307. Epub 2011 Sep 19. Eur J Immunol. 2011. PMID: 21805465 Free article.
317 results