Westendorp RG - Search Results

1

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs.

Ye K, Beekman M, Lameijer EW, Zhang Y, Moed MH, van den Akker EB, Deelen J, Houwing-Duistermaat JJ, Kremer D, Anvar SY, Laros JF, Jones D, Raine K, Blackburne B, Potluri S, Long Q, Guryev V, van der Breggen R, Westendorp RG, 't Hoen PA, den Dunnen J, van Ommen GJ, Willemsen G, Pitts SJ, Cox DR, Ning Z, Boomsma DI, Slagboom PE. Ye K, et al. Among authors: westendorp rg. Twin Res Hum Genet. 2013 Dec;16(6):1026-32. doi: 10.1017/thg.2013.73. Epub 2013 Nov 4. Twin Res Hum Genet. 2013. PMID: 24182360

2

Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age.

Heijmans BT, Slagboom PE, Gussekloo J, Droog S, Lagaay AM, Kluft C, Knook DL, Westendorp RG. Heijmans BT, et al. Among authors: westendorp rg. Am J Med Genet. 2002 Jan 22;107(3):201-8. doi: 10.1002/ajmg.10142. Am J Med Genet. 2002. PMID: 11807900

3

A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer.

Heijmans BT, Boer JM, Suchiman HE, Cornelisse CJ, Westendorp RG, Kromhout D, Feskens EJ, Slagboom PE. Heijmans BT, et al. Among authors: westendorp rg. Cancer Res. 2003 Mar 15;63(6):1249-53. Cancer Res. 2003. PMID: 12649184

4

Variation in the SHC1 gene and longevity in humans.

Mooijaart SP, van Heemst D, Schreuder J, van Gerwen S, Beekman M, Brandt BW, Eline Slagboom P, Westendorp RG; 'Long Life' Study Group. Mooijaart SP, et al. Among authors: westendorp rg. Exp Gerontol. 2004 Feb;39(2):263-8. doi: 10.1016/j.exger.2003.10.001. Exp Gerontol. 2004. PMID: 15036421

5

Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family?

Brandt BW, Zwaan BJ, Beekman M, Westendorp RG, Slagboom PE. Brandt BW, et al. Among authors: westendorp rg. Bioessays. 2005 Mar;27(3):339-46. doi: 10.1002/bies.20161. Bioessays. 2005. PMID: 15714554 Review.

6

Reduced insulin/IGF-1 signalling and human longevity.

van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG. van Heemst D, et al. Among authors: westendorp rg. Aging Cell. 2005 Apr;4(2):79-85. doi: 10.1111/j.1474-9728.2005.00148.x. Aging Cell. 2005. PMID: 15771611 Free article.

7

Human cytokine response to ex vivo amyloid-beta stimulation is mediated by genetic factors.

Posthuma D, Meulenbelt I, de Craen AJ, de Geus EJ, Slagboom PE, Boomsma DI, Westendorp RG. Posthuma D, et al. Among authors: westendorp rg. Twin Res Hum Genet. 2005 Apr;8(2):132-7. doi: 10.1375/1832427053738728. Twin Res Hum Genet. 2005. PMID: 15901476

8

Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study.

Schoenmaker M, de Craen AJ, de Meijer PH, Beekman M, Blauw GJ, Slagboom PE, Westendorp RG. Schoenmaker M, et al. Among authors: westendorp rg. Eur J Hum Genet. 2006 Jan;14(1):79-84. doi: 10.1038/sj.ejhg.5201508. Eur J Hum Genet. 2006. PMID: 16251894

9

Impact of genetic variations in the WRN gene on age related pathologies and mortality.

Kuningas M, Slagboom PE, Westendorp RG, van Heemst D. Kuningas M, et al. Among authors: westendorp rg. Mech Ageing Dev. 2006 Mar;127(3):307-13. doi: 10.1016/j.mad.2005.11.005. Epub 2006 Jan 6. Mech Ageing Dev. 2006. PMID: 16405962

10

Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies.

Beekman M, Blauw GJ, Houwing-Duistermaat JJ, Brandt BW, Westendorp RG, Slagboom PE. Beekman M, et al. Among authors: westendorp rg. J Gerontol A Biol Sci Med Sci. 2006 Apr;61(4):355-62. doi: 10.1093/gerona/61.4.355. J Gerontol A Biol Sci Med Sci. 2006. PMID: 16611701

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