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AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer.
Dunne PD, McArt DG, Blayney JK, Kalimutho M, Greer S, Wang T, Srivastava S, Ong CW, Arthur K, Loughrey M, Redmond K, Longley DB, Salto-Tellez M, Johnston PG, Van Schaeybroeck S. Dunne PD, et al. Among authors: kalimutho m. Clin Cancer Res. 2014 Jan 1;20(1):164-75. doi: 10.1158/1078-0432.CCR-13-1354. Epub 2013 Oct 29. Clin Cancer Res. 2014. PMID: 24170546 Free PMC article.
ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer.
Van Schaeybroeck S, Kalimutho M, Dunne PD, Carson R, Allen W, Jithesh PV, Redmond KL, Sasazuki T, Shirasawa S, Blayney J, Michieli P, Fenning C, Lenz HJ, Lawler M, Longley DB, Johnston PG. Van Schaeybroeck S, et al. Among authors: kalimutho m. Cell Rep. 2014 Jun 26;7(6):1940-55. doi: 10.1016/j.celrep.2014.05.032. Epub 2014 Jun 12. Cell Rep. 2014. PMID: 24931611 Free article.
Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma.
Al-Ejeh F, Pajic M, Shi W, Kalimutho M, Miranda M, Nagrial AM, Chou A, Biankin AV, Grimmond SM; Australian Pancreatic Cancer Genome Initiative; Brown MP, Khanna KK. Al-Ejeh F, et al. Among authors: kalimutho m. Clin Cancer Res. 2014 Jun 15;20(12):3187-97. doi: 10.1158/1078-0432.CCR-14-0048. Epub 2014 May 16. Clin Cancer Res. 2014. PMID: 24838526
Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis.
Mittal D, Sinha D, Barkauskas D, Young A, Kalimutho M, Stannard K, Caramia F, Haibe-Kains B, Stagg J, Khanna KK, Loi S, Smyth MJ. Mittal D, et al. Among authors: kalimutho m. Cancer Res. 2016 Aug 1;76(15):4372-82. doi: 10.1158/0008-5472.CAN-16-0544. Epub 2016 May 24. Cancer Res. 2016. PMID: 27221704
COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis.
Hancock JL, Kalimutho M, Straube J, Lim M, Gresshoff I, Saunus JM, Lee JS, Lakhani SR, Simpson KJ, Bush AI, Anderson RL, Khanna KK. Hancock JL, et al. Among authors: kalimutho m. J Exp Clin Cancer Res. 2023 Apr 18;42(1):90. doi: 10.1186/s13046-023-02663-8. J Exp Clin Cancer Res. 2023. PMID: 37072858 Free PMC article.
Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
Kalimutho M, Bain AL, Mukherjee B, Nag P, Nanayakkara DM, Harten SK, Harris JL, Subramanian GN, Sinha D, Shirasawa S, Srihari S, Burma S, Khanna KK. Kalimutho M, et al. Mol Oncol. 2017 May;11(5):470-490. doi: 10.1002/1878-0261.12040. Epub 2017 Mar 27. Mol Oncol. 2017. PMID: 28173629 Free PMC article.
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