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Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.
Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M. Voloshanenko O, et al. Among authors: spang r. Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610. Nat Commun. 2013. PMID: 24162018 Free PMC article.
Refining Pathways: A Model Comparison Approach.
Moffa G, Erdmann G, Voloshanenko O, Hundsrucker C, Sadeh MJ, Boutros M, Spang R. Moffa G, et al. Among authors: spang r. PLoS One. 2016 Jun 1;11(6):e0155999. doi: 10.1371/journal.pone.0155999. eCollection 2016. PLoS One. 2016. PMID: 27248690 Free PMC article.
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Feist M, Schwarzfischer P, Heinrich P, Sun X, Kemper J, von Bonin F, Perez-Rubio P, Taruttis F, Rehberg T, Dettmer K, Gronwald W, Reinders J, Engelmann JC, Dudek J, Klapper W, Trümper L, Spang R, Oefner PJ, Kube D. Feist M, et al. Among authors: spang r. Nat Commun. 2018 Apr 17;9(1):1514. doi: 10.1038/s41467-018-03803-x. Nat Commun. 2018. PMID: 29666362 Free PMC article.
Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease.
Holler E, Butzhammer P, Schmid K, Hundsrucker C, Koestler J, Peter K, Zhu W, Sporrer D, Hehlgans T, Kreutz M, Holler B, Wolff D, Edinger M, Andreesen R, Levine JE, Ferrara JL, Gessner A, Spang R, Oefner PJ. Holler E, et al. Among authors: spang r. Biol Blood Marrow Transplant. 2014 May;20(5):640-5. doi: 10.1016/j.bbmt.2014.01.030. Epub 2014 Jan 31. Biol Blood Marrow Transplant. 2014. PMID: 24492144 Free PMC article.
Early dissemination seeds metastasis in breast cancer.
Hosseini H, Obradović MMS, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, Patwary N, Haunschild G, Gužvić M, Reimelt C, Grauvogl M, Eichner N, Weber F, Hartkopf AD, Taran FA, Brucker SY, Fehm T, Rack B, Buchholz S, Spang R, Meister G, Aguirre-Ghiso JA, Klein CA. Hosseini H, et al. Among authors: spang r. Nature. 2016 Dec 22;540(7634):552-558. doi: 10.1038/nature20785. Epub 2016 Dec 14. Nature. 2016. PMID: 27974799 Free PMC article.
TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity.
Riquelme P, Haarer J, Kammler A, Walter L, Tomiuk S, Ahrens N, Wege AK, Goecze I, Zecher D, Banas B, Spang R, Fändrich F, Lutz MB, Sawitzki B, Schlitt HJ, Ochando J, Geissler EK, Hutchinson JA. Riquelme P, et al. Among authors: spang r. Nat Commun. 2018 Jul 20;9(1):2858. doi: 10.1038/s41467-018-05167-8. Nat Commun. 2018. PMID: 30030423 Free PMC article.
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Sorrentino A, Menevse AN, Michels T, Volpin V, Durst FC, Sax J, Xydia M, Hussein A, Stamova S, Spoerl S, Heuschneider N, Muehlbauer J, Jeltsch KM, Rathinasamy A, Werner-Klein M, Breinig M, Mikietyn D, Kohler C, Poschke I, Purr S, Reidell O, Martins Freire C, Offringa R, Gebhard C, Spang R, Rehli M, Boutros M, Schmidl C, Khandelwal N, Beckhove P. Sorrentino A, et al. Among authors: spang r. J Immunother Cancer. 2022 May;10(5):e004258. doi: 10.1136/jitc-2021-004258. J Immunother Cancer. 2022. PMID: 35606086 Free PMC article.
Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis.
Hutchinson JA, Kronenberg K, Riquelme P, Wenzel JJ, Glehr G, Schilling HL, Zeman F, Evert K, Schmiedel M, Mickler M, Drexler K, Bitterer F, Cordero L, Beyer L, Bach C, Koestler J, Burkhardt R, Schlitt HJ, Hellwig D, Werner JM, Spang R, Schmidt B, Geissler EK, Haferkamp S. Hutchinson JA, et al. Among authors: spang r. Nat Commun. 2021 Mar 4;12(1):1439. doi: 10.1038/s41467-021-21572-y. Nat Commun. 2021. PMID: 33664251 Free PMC article.
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.
Minderjahn J, Schmidt A, Fuchs A, Schill R, Raithel J, Babina M, Schmidl C, Gebhard C, Schmidhofer S, Mendes K, Ratermann A, Glatz D, Nützel M, Edinger M, Hoffmann P, Spang R, Längst G, Imhof A, Rehli M. Minderjahn J, et al. Among authors: spang r. Nat Commun. 2020 Jan 21;11(1):402. doi: 10.1038/s41467-019-13960-2. Nat Commun. 2020. PMID: 31964861 Free PMC article.
164 results