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ERBB4 mutations that disrupt the neuregulin-ErbB4 pathway cause amyotrophic lateral sclerosis type 19.
Takahashi Y, Fukuda Y, Yoshimura J, Toyoda A, Kurppa K, Moritoyo H, Belzil VV, Dion PA, Higasa K, Doi K, Ishiura H, Mitsui J, Date H, Ahsan B, Matsukawa T, Ichikawa Y, Moritoyo T, Ikoma M, Hashimoto T, Kimura F, Murayama S, Onodera O, Nishizawa M, Yoshida M, Atsuta N, Sobue G; JaCALS; Fifita JA, Williams KL, Blair IP, Nicholson GA, Gonzalez-Perez P, Brown RH Jr, Nomoto M, Elenius K, Rouleau GA, Fujiyama A, Morishita S, Goto J, Tsuji S. Takahashi Y, et al. Among authors: elenius k. Am J Hum Genet. 2013 Nov 7;93(5):900-5. doi: 10.1016/j.ajhg.2013.09.008. Epub 2013 Oct 10. Am J Hum Genet. 2013. PMID: 24119685 Free PMC article.
Mutated ERBB4: a novel drug target in metastatic melanoma?
Kurppa K, Elenius K. Kurppa K, et al. Among authors: elenius k. Pigment Cell Melanoma Res. 2009 Dec;22(6):708-10. doi: 10.1111/j.1755-148X.2009.00635.x. Epub 2009 Sep 7. Pigment Cell Melanoma Res. 2009. PMID: 19735458 No abstract available.
Cell death or survival promoted by alternative isoforms of ErbB4.
Sundvall M, Veikkolainen V, Kurppa K, Salah Z, Tvorogov D, van Zoelen EJ, Aqeilan R, Elenius K. Sundvall M, et al. Among authors: elenius k. Mol Biol Cell. 2010 Dec;21(23):4275-86. doi: 10.1091/mbc.E10-04-0332. Epub 2010 Oct 13. Mol Biol Cell. 2010. PMID: 20943952 Free PMC article.
Activating ERBB4 mutations in non-small cell lung cancer.
Kurppa KJ, Denessiouk K, Johnson MS, Elenius K. Kurppa KJ, et al. Among authors: elenius k. Oncogene. 2016 Mar 10;35(10):1283-91. doi: 10.1038/onc.2015.185. Epub 2015 Jun 8. Oncogene. 2016. PMID: 26050618
An Unbiased Functional Genetics Screen Identifies Rare Activating ERBB4 Mutations.
Chakroborty D, Ojala VK, Knittle AM, Drexler J, Tamirat MZ, Ruzicka R, Bosch K, Woertl J, Schmittner S, Elo LL, Johnson MS, Kurppa KJ, Solca F, Elenius K. Chakroborty D, et al. Among authors: elenius k. Cancer Res Commun. 2022 Jan 7;2(1):10-27. doi: 10.1158/2767-9764.CRC-21-0021. eCollection 2022 Jan. Cancer Res Commun. 2022. PMID: 36860695 Free PMC article.
Potential of ErbB4 antibodies for cancer therapy.
Hollmén M, Elenius K. Hollmén M, et al. Among authors: elenius k. Future Oncol. 2010 Jan;6(1):37-53. doi: 10.2217/fon.09.144. Future Oncol. 2010. PMID: 20021208 Review.
127 results