Bauer DE - Search Results

1

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH. Bauer DE, et al. Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088. Science. 2013. PMID: 24115442 Free PMC article.

2

Update on fetal hemoglobin gene regulation in hemoglobinopathies.

Bauer DE, Orkin SH. Bauer DE, et al. Curr Opin Pediatr. 2011 Feb;23(1):1-8. doi: 10.1097/MOP.0b013e3283420fd0. Curr Opin Pediatr. 2011. PMID: 21157349 Free PMC article. Review.

3

Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.

Bauer DE, Kamran SC, Orkin SH. Bauer DE, et al. Blood. 2012 Oct 11;120(15):2945-53. doi: 10.1182/blood-2012-06-292078. Epub 2012 Aug 17. Blood. 2012. PMID: 22904296 Free PMC article. Review.

4

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.

Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF. Sankaran VG, et al. Among authors: bauer de. Genes Dev. 2012 Sep 15;26(18):2075-87. doi: 10.1101/gad.197020.112. Epub 2012 Aug 28. Genes Dev. 2012. PMID: 22929040 Free PMC article.

5

Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis.

Xu J, Shao Z, Glass K, Bauer DE, Pinello L, Van Handel B, Hou S, Stamatoyannopoulos JA, Mikkola HK, Yuan GC, Orkin SH. Xu J, et al. Among authors: bauer de. Dev Cell. 2012 Oct 16;23(4):796-811. doi: 10.1016/j.devcel.2012.09.003. Epub 2012 Oct 4. Dev Cell. 2012. PMID: 23041383 Free PMC article.

6

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.

Xu J, Bauer DE, Kerenyi MA, Vo TD, Hou S, Hsu YJ, Yao H, Trowbridge JJ, Mandel G, Orkin SH. Xu J, et al. Among authors: bauer de. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6518-23. doi: 10.1073/pnas.1303976110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576758 Free PMC article.

7

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

Canver MC, Bauer DE, Dass A, Yien YY, Chung J, Masuda T, Maeda T, Paw BH, Orkin SH. Canver MC, et al. Among authors: bauer de. J Biol Chem. 2014 Aug 1;289(31):21312-24. doi: 10.1074/jbc.M114.564625. Epub 2014 Jun 6. J Biol Chem. 2014. PMID: 24907273 Free PMC article.

8

Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9.

Bauer DE, Canver MC, Orkin SH. Bauer DE, et al. J Vis Exp. 2015 Jan 3;(95):e52118. doi: 10.3791/52118. J Vis Exp. 2015. PMID: 25549070 Free PMC article.

9

The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.

Chung J, Bauer DE, Ghamari A, Nizzi CP, Deck KM, Kingsley PD, Yien YY, Huston NC, Chen C, Schultz IJ, Dalton AJ, Wittig JG, Palis J, Orkin SH, Lodish HF, Eisenstein RS, Cantor AB, Paw BH. Chung J, et al. Among authors: bauer de. Sci Signal. 2015 Apr 14;8(372):ra34. doi: 10.1126/scisignal.aaa5903. Sci Signal. 2015. PMID: 25872869 Free PMC article.

10

Embryonic stem cells as sources of donor-independent platelets.

Canver MC, Bauer DE, Orkin SH. Canver MC, et al. Among authors: bauer de. J Clin Invest. 2015 Jun;125(6):2261-3. doi: 10.1172/JCI82348. Epub 2015 May 11. J Clin Invest. 2015. PMID: 25961451 Free PMC article.

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