Obaya A - Search Results

1

Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas.

Fanjul-Fernández M, Quesada V, Cabanillas R, Cadiñanos J, Fontanil T, Obaya A, Ramsay AJ, Llorente JL, Astudillo A, Cal S, López-Otín C. Fanjul-Fernández M, et al. Among authors: obaya a. Nat Commun. 2013;4:2531. doi: 10.1038/ncomms3531. Nat Commun. 2013. PMID: 24100690 Free article.

2

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

Cal S, Obaya AJ, Llamazares M, Garabaya C, Quesada V, López-Otín C. Cal S, et al. Gene. 2002 Jan 23;283(1-2):49-62. doi: 10.1016/s0378-1119(01)00861-7. Gene. 2002. PMID: 11867212

3

The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway.

Llamazares M, Obaya AJ, Moncada-Pazos A, Heljasvaara R, Espada J, López-Otín C, Cal S. Llamazares M, et al. Among authors: obaya aj. J Cell Sci. 2007 Oct 15;120(Pt 20):3544-52. doi: 10.1242/jcs.005751. Epub 2007 Sep 25. J Cell Sci. 2007. PMID: 17895370

4

Accelerated ageing: from mechanism to therapy through animal models.

Osorio FG, Obaya AJ, López-Otín C, Freije JM. Osorio FG, et al. Transgenic Res. 2009 Feb;18(1):7-15. doi: 10.1007/s11248-008-9226-z. Epub 2008 Nov 18. Transgenic Res. 2009. PMID: 19015945 Review.

5

Genetic inactivation of ADAMTS15 metalloprotease in human colorectal cancer.

Viloria CG, Obaya AJ, Moncada-Pazos A, Llamazares M, Astudillo A, Capellá G, Cal S, López-Otín C. Viloria CG, et al. Among authors: obaya aj. Cancer Res. 2009 Jun 1;69(11):4926-34. doi: 10.1158/0008-5472.CAN-08-4155. Epub 2009 May 19. Cancer Res. 2009. PMID: 19458070 Free article.

6

The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer.

Moncada-Pazos A, Obaya AJ, Fraga MF, Viloria CG, Capellá G, Gausachs M, Esteller M, López-Otín C, Cal S. Moncada-Pazos A, et al. Among authors: obaya aj. J Cell Sci. 2009 Aug 15;122(Pt 16):2906-13. doi: 10.1242/jcs.050468. Epub 2009 Jul 28. J Cell Sci. 2009. PMID: 19638407

7

Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer.

Lara E, Calvanese V, Huidobro C, Fernández AF, Moncada-Pazos A, Obaya AJ, Aguilera O, González-Sancho JM, Sánchez L, Astudillo A, Muñoz A, López-Otín C, Esteller M, Fraga MF. Lara E, et al. Among authors: obaya aj. Mol Cancer. 2010 Jun 30;9:170. doi: 10.1186/1476-4598-9-170. Mol Cancer. 2010. PMID: 20591152 Free PMC article.

8

The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities.

Moncada-Pazos A, Obaya AJ, Viloria CG, López-Otín C, Cal S. Moncada-Pazos A, et al. Among authors: obaya aj. J Mol Med (Berl). 2011 Jun;89(6):611-9. doi: 10.1007/s00109-011-0741-7. Epub 2011 Mar 2. J Mol Med (Berl). 2011. PMID: 21365186

9

A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer.

Huidobro C, Urdinguio RG, Rodríguez RM, Mangas C, Calvanese V, Martínez-Camblor P, Ferrero C, Parra-Blanco A, Rodrigo L, Obaya AJ, Suárez-Fernández L, Astudillo A, Hernando H, Ballestar E, Fernández AF, Fraga MF. Huidobro C, et al. Among authors: obaya aj. Eur J Cancer. 2012 Sep;48(14):2270-81. doi: 10.1016/j.ejca.2011.12.019. Epub 2012 Jan 13. Eur J Cancer. 2012. PMID: 22244828

10

The dual role of fibulins in tumorigenesis.

Obaya AJ, Rua S, Moncada-Pazos A, Cal S. Obaya AJ, et al. Cancer Lett. 2012 Dec 28;325(2):132-8. doi: 10.1016/j.canlet.2012.06.019. Epub 2012 Jul 7. Cancer Lett. 2012. PMID: 22781395

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