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Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo.
Maussang D, Mujić-Delić A, Descamps FJ, Stortelers C, Vanlandschoot P, Stigter-van Walsum M, Vischer HF, van Roy M, Vosjan M, Gonzalez-Pajuelo M, van Dongen GA, Merchiers P, van Rompaey P, Smit MJ. Maussang D, et al. Among authors: van roy m. J Biol Chem. 2013 Oct 11;288(41):29562-72. doi: 10.1074/jbc.M113.498436. Epub 2013 Aug 26. J Biol Chem. 2013. PMID: 23979133 Free PMC article.
Human Epidermal Growth Factor Receptor 3-Specific Tumor Uptake and Biodistribution of 89Zr-MSB0010853 Visualized by Real-Time and Noninvasive PET Imaging.
Warnders FJ, Terwisscha van Scheltinga AGT, Knuehl C, van Roy M, de Vries EFJ, Kosterink JGW, de Vries EGE, Lub-de Hooge MN. Warnders FJ, et al. Among authors: van roy m. J Nucl Med. 2017 Aug;58(8):1210-1215. doi: 10.2967/jnumed.116.181586. Epub 2017 Mar 30. J Nucl Med. 2017. PMID: 28360206 Free article.
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium.
Van Hauwermeiren F, Armaka M, Karagianni N, Kranidioti K, Vandenbroucke RE, Loges S, Van Roy M, Staelens J, Puimège L, Palagani A, Berghe WV, Victoratos P, Carmeliet P, Libert C, Kollias G. Van Hauwermeiren F, et al. Among authors: van roy m. J Clin Invest. 2013 Jun;123(6):2590-603. doi: 10.1172/JCI65624. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676465 Free PMC article.
The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis.
Van Roy M, Ververken C, Beirnaert E, Hoefman S, Kolkman J, Vierboom M, Breedveld E, 't Hart B, Poelmans S, Bontinck L, Hemeryck A, Jacobs S, Baumeister J, Ulrichts H. Van Roy M, et al. Arthritis Res Ther. 2015 May 20;17(1):135. doi: 10.1186/s13075-015-0651-0. Arthritis Res Ther. 2015. PMID: 25994180 Free PMC article.
18 results