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Fragment-based ligand design of novel potent inhibitors of tankyrases.
Larsson EA, Jansson A, Ng FM, Then SW, Panicker R, Liu B, Sangthongpitag K, Pendharkar V, Tai SJ, Hill J, Dan C, Ho SY, Cheong WW, Poulsen A, Blanchard S, Lin GR, Alam J, Keller TH, Nordlund P. Larsson EA, et al. Among authors: then sw. J Med Chem. 2013 Jun 13;56(11):4497-508. doi: 10.1021/jm400211f. Epub 2013 Jun 4. J Med Chem. 2013. PMID: 23672613
Application of Fragment-Based Drug Discovery against DNA Gyrase B.
Chen GY, Ng FM, Tan YW, Poulsen A, Seetoh W, Lin G, Kang C, Then SW, Ahmad NH, Wong YL, Ng HQ, Chia CSB, Lau QY, Hill J, Hung AW, Keller TH. Chen GY, et al. Among authors: then sw. Chempluschem. 2015 Aug;80(8):1250-1254. doi: 10.1002/cplu.201500197. Epub 2015 Jun 24. Chempluschem. 2015. PMID: 31973307
Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.
De Robertis A, Valensin S, Rossi M, Tunici P, Verani M, De Rosa A, Giordano C, Varrone M, Nencini A, Pratelli C, Benicchi T, Bakker A, Hill J, Sangthongpitag K, Pendharkar V, Liu B, Ng FM, Then SW, Jing Tai S, Cheong SM, He X, Caricasole A, Salerno M. De Robertis A, et al. Among authors: then sw. Mol Cancer Ther. 2013 Jul;12(7):1180-9. doi: 10.1158/1535-7163.MCT-12-1176-T. Epub 2013 Apr 25. Mol Cancer Ther. 2013. PMID: 23619303 Free PMC article.