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AT1 antagonists: a patent review (2008 - 2012).
Mavromoustakos T, Agelis G, Durdagi S. Mavromoustakos T, et al. Expert Opin Ther Pat. 2013 Nov;23(11):1483-94. doi: 10.1517/13543776.2013.830104. Epub 2013 Aug 23. Expert Opin Ther Pat. 2013. PMID: 23968548 Review.
Design, synthesis and biological evaluation of cyclic angiotensin II analogues with 3,5 side-chain bridges. Role of C-terminal aromatic residue and ring cluster for activity and implications in the drug design of AT1 non-peptide antagonists.
Roumelioti P, Polevaya L, Zoumpoulakis P, Giatas N, Mutule I, Keivish T, Zoga A, Vlahakos D, Iliodromitis E, Kremastinos D, Grdadolnik SG, Mavromoustakos T, Matsoukas J. Roumelioti P, et al. Among authors: mavromoustakos t. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2627-33. doi: 10.1016/s0960-894x(02)00474-2. Bioorg Med Chem Lett. 2002. PMID: 12182875
Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy.
Zoumpoulakis P, Zoga A, Roumelioti P, Giatas N, Grdadolnik SG, Iliodromitis E, Vlahakos D, Kremastinos D, Matsoukas JM, Mavromoustakos T. Zoumpoulakis P, et al. Among authors: mavromoustakos t. J Pharm Biomed Anal. 2003 Apr 1;31(5):833-44. doi: 10.1016/s0731-7085(02)00655-6. J Pharm Biomed Anal. 2003. PMID: 12684096
Design and synthesis of novel antihypertensive drugs.
Moutevelis-Minakakis P, Gianni M, Stougiannou H, Zoumpoulakis P, Zoga A, Vlahakos AD, Iliodromitis E, Mavromoustakos T. Moutevelis-Minakakis P, et al. Among authors: mavromoustakos t. Bioorg Med Chem Lett. 2003 May 19;13(10):1737-40. doi: 10.1016/s0960-894x(03)00251-8. Bioorg Med Chem Lett. 2003. PMID: 12729654
The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2.
Durdagi S, Kapou A, Kourouli T, Andreou T, Nikas SP, Nahmias VR, Papahatjis DP, Papadopoulos MG, Mavromoustakos T. Durdagi S, et al. Among authors: mavromoustakos t. J Med Chem. 2007 Jun 14;50(12):2875-85. doi: 10.1021/jm0610705. Epub 2007 May 24. J Med Chem. 2007. PMID: 17521177
243 results