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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.
McGowan S, Porter CJ, Lowther J, Stack CM, Golding SJ, Skinner-Adams TS, Trenholme KR, Teuscher F, Donnelly SM, Grembecka J, Mucha A, Kafarski P, Degori R, Buckle AM, Gardiner DL, Whisstock JC, Dalton JP. McGowan S, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2537-42. doi: 10.1073/pnas.0807398106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196988 Free PMC article.
Structure of granzyme C reveals an unusual mechanism of protease autoinhibition.
Kaiserman D, Buckle AM, Van Damme P, Irving JA, Law RH, Matthews AY, Bashtannyk-Puhalovich T, Langendorf C, Thompson P, Vandekerckhove J, Gevaert K, Whisstock JC, Bird PI. Kaiserman D, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5587-92. doi: 10.1073/pnas.0811968106. Epub 2009 Mar 19. Proc Natl Acad Sci U S A. 2009. PMID: 19299505 Free PMC article.
X-ray crystal structure of the streptococcal specific phage lysin PlyC.
McGowan S, Buckle AM, Mitchell MS, Hoopes JT, Gallagher DT, Heselpoth RD, Shen Y, Reboul CF, Law RH, Fischetti VA, Whisstock JC, Nelson DC. McGowan S, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12752-7. doi: 10.1073/pnas.1208424109. Epub 2012 Jul 17. Proc Natl Acad Sci U S A. 2012. PMID: 22807482 Free PMC article.
Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Ellisdon AM, Reboul CF, Panjikar S, Huynh K, Oellig CA, Winter KL, Dunstone MA, Hodgson WC, Seymour J, Dearden PK, Tweten RK, Whisstock JC, McGowan S. Ellisdon AM, et al. Among authors: whisstock jc. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15360-5. doi: 10.1073/pnas.1507622112. Epub 2015 Dec 1. Proc Natl Acad Sci U S A. 2015. PMID: 26627714 Free PMC article.
268 results