Mirelman D - Search Results

1

Glutamate oxaloacetate transaminase: a new key in the dysregulation of glutamate in migraine patients.

Campos F, Sobrino T, Pérez-Mato M, Rodríguez-Osorio X, Leira R, Blanco M, Mirelman D, Castillo J. Campos F, et al. Among authors: mirelman d. Cephalalgia. 2013 Oct;33(14):1148-54. doi: 10.1177/0333102413487444. Epub 2013 May 14. Cephalalgia. 2013. PMID: 23674828

2

Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia.

Pérez-Mato M, Ramos-Cabrer P, Sobrino T, Blanco M, Ruban A, Mirelman D, Menendez P, Castillo J, Campos F. Pérez-Mato M, et al. Among authors: mirelman d. Cell Death Dis. 2014 Jan 9;5(1):e992. doi: 10.1038/cddis.2013.507. Cell Death Dis. 2014. PMID: 24407245 Free PMC article.

3

Inhibition of endogenous blood glutamate oxaloacetate transaminase enhances the ischemic damage.

Dopico-López A, Pérez-Mato M, da Silva-Candal A, Iglesias-Rey R, Rabinkov A, Bugallo-Casal A, Sobrino T, Mirelman D, Castillo J, Campos F. Dopico-López A, et al. Among authors: mirelman d. Transl Res. 2021 Apr;230:68-81. doi: 10.1016/j.trsl.2020.10.004. Epub 2020 Oct 22. Transl Res. 2021. PMID: 33132087

4

Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality.

da Silva-Candal A, Vieites-Prado A, Gutiérrez-Fernández M, Rey RI, Argibay B, Mirelman D, Sobrino T, Rodríguez-Frutos B, Castillo J, Campos F. da Silva-Candal A, et al. Among authors: mirelman d. J Cereb Blood Flow Metab. 2015 Jul;35(7):1206-12. doi: 10.1038/jcbfm.2015.28. Epub 2015 Mar 4. J Cereb Blood Flow Metab. 2015. PMID: 25735920 Free PMC article.

5

A novel mechanism of neuroprotection: Blood glutamate grabber.

Castillo J, Loza MI, Mirelman D, Brea J, Blanco M, Sobrino T, Campos F. Castillo J, et al. Among authors: mirelman d. J Cereb Blood Flow Metab. 2016 Feb;36(2):292-301. doi: 10.1177/0271678X15606721. Epub 2015 Oct 2. J Cereb Blood Flow Metab. 2016. PMID: 26661174 Free PMC article. Review.

6

MRS of brain metabolite levels demonstrates the ability of scavenging of excess brain glutamate to protect against nerve agent induced seizures.

Ruban A, Biton IE, Markovich A, Mirelman D. Ruban A, et al. Among authors: mirelman d. Int J Mol Sci. 2015 Feb 2;16(2):3226-36. doi: 10.3390/ijms16023226. Int J Mol Sci. 2015. PMID: 25648322 Free PMC article.

7

Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery.

Miron T, Mironchik M, Mirelman D, Wilchek M, Rabinkov A. Miron T, et al. Among authors: mirelman d. Mol Cancer Ther. 2003 Dec;2(12):1295-301. Mol Cancer Ther. 2003. PMID: 14707270

8

Alliinase (alliin lyase) from garlic (Alliium sativum) is glycosylated at ASN146 and forms a complex with a garlic mannose-specific lectin.

Rabinkov A, Wilchek M, Mirelman D. Rabinkov A, et al. Among authors: mirelman d. Glycoconj J. 1995 Oct;12(5):690-8. doi: 10.1007/BF00731266. Glycoconj J. 1995. PMID: 8595261

9

Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.

Arditti FD, Rabinkov A, Miron T, Reisner Y, Berrebi A, Wilchek M, Mirelman D. Arditti FD, et al. Among authors: mirelman d. Mol Cancer Ther. 2005 Feb;4(2):325-31. Mol Cancer Ther. 2005. PMID: 15713903

10

Conjugates of daidzein-alliinase as a targeted pro-drug enzyme system against ovarian carcinoma.

Appel E, Rabinkov A, Neeman M, Kohen F, Mirelman D. Appel E, et al. Among authors: mirelman d. J Drug Target. 2011 Jun;19(5):326-35. doi: 10.3109/1061186X.2010.504265. Epub 2010 Aug 3. J Drug Target. 2011. PMID: 20678009

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