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Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.
Humblet-Baron S, Sather B, Anover S, Becker-Herman S, Kasprowicz DJ, Khim S, Nguyen T, Hudkins-Loya K, Alpers CE, Ziegler SF, Ochs H, Torgerson T, Campbell DJ, Rawlings DJ. Humblet-Baron S, et al. Among authors: rawlings dj. J Clin Invest. 2007 Feb;117(2):407-18. doi: 10.1172/JCI29539. Epub 2007 Jan 11. J Clin Invest. 2007. PMID: 17218989 Free PMC article.
Myc stimulates B lymphocyte differentiation and amplifies calcium signaling.
Habib T, Park H, Tsang M, de Alborán IM, Nicks A, Wilson L, Knoepfler PS, Andrews S, Rawlings DJ, Eisenman RN, Iritani BM. Habib T, et al. Among authors: rawlings dj. J Cell Biol. 2007 Nov 19;179(4):717-31. doi: 10.1083/jcb.200704173. Epub 2007 Nov 12. J Cell Biol. 2007. PMID: 17998397 Free PMC article.
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: rawlings dj. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.
G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity.
Misra RS, Shi G, Moreno-Garcia ME, Thankappan A, Tighe M, Mousseau B, Kusser K, Becker-Herman S, Hudkins KL, Dunn R, Kehry MR, Migone TS, Marshak-Rothstein A, Simon M, Randall TD, Alpers CE, Liggitt D, Rawlings DJ, Lund FE. Misra RS, et al. Among authors: rawlings dj. J Exp Med. 2010 Aug 2;207(8):1775-89. doi: 10.1084/jem.20092735. Epub 2010 Jul 12. J Exp Med. 2010. PMID: 20624888 Free PMC article.
WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity.
Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ. Becker-Herman S, et al. Among authors: rawlings dj. J Exp Med. 2011 Sep 26;208(10):2033-42. doi: 10.1084/jem.20110200. Epub 2011 Aug 29. J Exp Med. 2011. PMID: 21875954 Free PMC article.
257 results