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Predictors of renal replacement therapy in acute kidney injury.
Koziolek MJ, Datta RR, Mattes H, Jung K, Heise D, Streich JH, Mühlhausen J, Mueller GA, Dihazi H. Koziolek MJ, et al. Among authors: mattes h. Nephron Extra. 2012 Sep 21;2(1):247-55. doi: 10.1159/000342257. Print 2012 Jan. Nephron Extra. 2012. PMID: 23599703 Free PMC article.
Optimizing a Weakly Binding Fragment into a Potent RORγt Inverse Agonist with Efficacy in an in Vivo Inflammation Model.
Carcache DA, Vulpetti A, Kallen J, Mattes H, Orain D, Stringer R, Vangrevelinghe E, Wolf RM, Kaupmann K, Ottl J, Dawson J, Cooke NG, Hoegenauer K, Billich A, Wagner J, Guntermann C, Hintermann S. Carcache DA, et al. Among authors: mattes h. J Med Chem. 2018 Aug 9;61(15):6724-6735. doi: 10.1021/acs.jmedchem.8b00529. Epub 2018 Jul 24. J Med Chem. 2018. PMID: 29990434
Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors.
Glatthar R, Stojanovic A, Troxler T, Mattes H, Möbitz H, Beerli R, Blanz J, Gassmann E, Drückes P, Fendrich G, Gutmann S, Martiny-Baron G, Spence F, Hornfeld J, Peel JE, Sparrer H. Glatthar R, et al. Among authors: mattes h. J Med Chem. 2016 Aug 25;59(16):7544-60. doi: 10.1021/acs.jmedchem.6b00598. Epub 2016 Aug 17. J Med Chem. 2016. PMID: 27502541
The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold.
Gutmann S, Hinniger A, Fendrich G, Drückes P, Antz S, Mattes H, Möbitz H, Ofner S, Schmiedeberg N, Stojanovic A, Rieffel S, Strauss A, Troxler T, Glatthar R, Sparrer H. Gutmann S, et al. Among authors: mattes h. J Biol Chem. 2015 Jun 12;290(24):15210-8. doi: 10.1074/jbc.M115.648097. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918157 Free PMC article.
27 results