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High-level semi-synthetic production of the potent antimalarial artemisinin.
Nature. 2013 Apr 25;496(7446):528-32. doi: 10.1038/nature12051. Epub 2013 Apr 10.
Nature. 2013.
PMID: 23575629
Functional genomics and the biosynthesis of artemisinin.
Covello PS, Teoh KH, Polichuk DR, Reed DW, Nowak G.
Covello PS, et al. Among authors: polichuk dr.
Phytochemistry. 2007 Jul;68(14):1864-71. doi: 10.1016/j.phytochem.2007.02.016. Epub 2007 Mar 30.
Phytochemistry. 2007.
PMID: 17399751
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Artemisia annua L. (Asteraceae) trichome-specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin.
Teoh KH, Polichuk DR, Reed DW, Nowak G, Covello PS.
Teoh KH, et al. Among authors: polichuk dr.
FEBS Lett. 2006 Feb 20;580(5):1411-6. doi: 10.1016/j.febslet.2006.01.065. Epub 2006 Jan 30.
FEBS Lett. 2006.
PMID: 16458889
Free article.
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A glandular trichome-specific monoterpene alcohol dehydrogenase from Artemisia annua.
Polichuk DR, Zhang Y, Reed DW, Schmidt JF, Covello PS.
Polichuk DR, et al.
Phytochemistry. 2010 Aug;71(11-12):1264-9. doi: 10.1016/j.phytochem.2010.04.026. Epub 2010 Jun 4.
Phytochemistry. 2010.
PMID: 20621795
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Mechanistic study of an improbable reaction: alkene dehydrogenation by the delta12 acetylenase of Crepis alpina.
Reed DW, Polichuk DR, Buist PH, Ambrose SJ, Sasata RJ, Savile CK, Ross AR, Covello PS.
Reed DW, et al. Among authors: polichuk dr.
J Am Chem Soc. 2003 Sep 3;125(35):10635-40. doi: 10.1021/ja036489o.
J Am Chem Soc. 2003.
PMID: 12940747
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Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members.
Kharenko OA, Polichuk D, Nelson KM, Abrams SR, Loewen MC.
Kharenko OA, et al.
J Biochem. 2013 Oct;154(4):383-91. doi: 10.1093/jb/mvt067. Epub 2013 Aug 23.
J Biochem. 2013.
PMID: 23975754
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