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Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma.
Broniscer A, Baker SD, Wetmore C, Pai Panandiker AS, Huang J, Davidoff AM, Onar-Thomas A, Panetta JC, Chin TK, Merchant TE, Baker JN, Kaste SC, Gajjar A, Stewart CF. Broniscer A, et al. Among authors: huang j. Clin Cancer Res. 2013 Jun 1;19(11):3050-8. doi: 10.1158/1078-0432.CCR-13-0306. Epub 2013 Mar 27. Clin Cancer Res. 2013. PMID: 23536435 Free PMC article. Clinical Trial.
Exposure-Toxicity Association of Cyclophosphamide and Its Metabolites in Infants and Young Children with Primary Brain Tumors: Implications for Dosing.
Campagne O, Zhong B, Nair S, Lin T, Huang J, Onar-Thomas A, Robinson G, Gajjar A, Stewart CF. Campagne O, et al. Among authors: huang j. Clin Cancer Res. 2020 Apr 1;26(7):1563-1573. doi: 10.1158/1078-0432.CCR-19-2685. Epub 2019 Dec 3. Clin Cancer Res. 2020. PMID: 31796512 Free PMC article. Clinical Trial.
Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma.
Broniscer A, Jia S, Mandrell B, Hamideh D, Huang J, Onar-Thomas A, Gajjar A, Raimondi SC, Tatevossian RG, Stewart CF. Broniscer A, et al. Among authors: huang j. Pediatr Blood Cancer. 2018 Jul;65(7):e27035. doi: 10.1002/pbc.27035. Epub 2018 Mar 7. Pediatr Blood Cancer. 2018. PMID: 29512900 Free PMC article. Clinical Trial.
Pharmacokinetic basis for dosing high-dose methotrexate in infants and young children with malignant brain tumours.
Panetta JC, Roberts JK, Huang J, Lin T, Daryani VM, Harstead KE, Patel YT, Onar-Thomas A, Campagne O, Ward DA, Broniscer A, Robinson G, Gajjar A, Stewart CF. Panetta JC, et al. Among authors: huang j. Br J Clin Pharmacol. 2020 Feb;86(2):362-371. doi: 10.1111/bcp.14160. Epub 2020 Jan 8. Br J Clin Pharmacol. 2020. PMID: 31657864 Free PMC article.
A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).
Van Mater D, Gururangan S, Becher O, Campagne O, Leary S, Phillips JJ, Huang J, Lin T, Poussaint TY, Goldman S, Baxter P, Dhall G, Robinson G, DeWire-Schottmiller M, Hwang EI, Stewart CF, Onar-Thomas A, Dunkel IJ, Fouladi M. Van Mater D, et al. Among authors: huang j. Pediatr Blood Cancer. 2021 Apr;68(4):e28879. doi: 10.1002/pbc.28879. Epub 2021 Jan 6. Pediatr Blood Cancer. 2021. PMID: 33405376 Free PMC article. Clinical Trial.
Phase I study using crenolanib to target PDGFR kinase in children and young adults with newly diagnosed DIPG or recurrent high-grade glioma, including DIPG.
Tinkle CL, Broniscer A, Chiang J, Campagne O, Huang J, Orr BA, Li X, Patay Z, Zhang J, Baker SJ, Merchant TE, Jain V, Onar-Thomas A, Stewart CF, Wetmore C, Gajjar A. Tinkle CL, et al. Among authors: huang j. Neurooncol Adv. 2021 Dec 1;3(1):vdab179. doi: 10.1093/noajnl/vdab179. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34993482 Free PMC article.
Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average-risk or high-risk medulloblastoma.
Gurney JG, Bass JK, Onar-Thomas A, Huang J, Chintagumpala M, Bouffet E, Hassall T, Gururangan S, Heath JA, Kellie S, Cohn R, Fisher MJ, Panandiker AP, Merchant TE, Srinivasan A, Wetmore C, Qaddoumi I, Stewart CF, Armstrong GT, Broniscer A, Gajjar A. Gurney JG, et al. Among authors: huang j. Neuro Oncol. 2014 Jun;16(6):848-55. doi: 10.1093/neuonc/not241. Epub 2014 Jan 10. Neuro Oncol. 2014. PMID: 24414535 Free PMC article. Clinical Trial.
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