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Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway.
Lai L, Yan L, Gao S, Hu CL, Ge H, Davidow A, Park M, Bravo C, Iwatsubo K, Ishikawa Y, Auwerx J, Sinclair DA, Vatner SF, Vatner DE. Lai L, et al. Among authors: iwatsubo k. Circulation. 2013 Apr 23;127(16):1692-701. doi: 10.1161/CIRCULATIONAHA.112.001212. Epub 2013 Mar 27. Circulation. 2013. PMID: 23536361 Free PMC article.
Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress.
Okumura S, Vatner DE, Kurotani R, Bai Y, Gao S, Yuan Z, Iwatsubo K, Ulucan C, Kawabe J, Ghosh K, Vatner SF, Ishikawa Y. Okumura S, et al. Among authors: iwatsubo k. Circulation. 2007 Oct 16;116(16):1776-83. doi: 10.1161/CIRCULATIONAHA.107.698662. Epub 2007 Sep 24. Circulation. 2007. PMID: 17893275
Adenylyl cyclase type 5 protein expression during cardiac development and stress.
Hu CL, Chandra R, Ge H, Pain J, Yan L, Babu G, Depre C, Iwatsubo K, Ishikawa Y, Sadoshima J, Vatner SF, Vatner DE. Hu CL, et al. Among authors: iwatsubo k. Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1776-82. doi: 10.1152/ajpheart.00050.2009. Epub 2009 Sep 4. Am J Physiol Heart Circ Physiol. 2009. PMID: 19734365 Free PMC article.
Adenylyl cyclase type 5 in cardiac disease, metabolism, and aging.
Vatner SF, Park M, Yan L, Lee GJ, Lai L, Iwatsubo K, Ishikawa Y, Pessin J, Vatner DE. Vatner SF, et al. Among authors: iwatsubo k. Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H1-8. doi: 10.1152/ajpheart.00080.2013. Epub 2013 Apr 26. Am J Physiol Heart Circ Physiol. 2013. PMID: 23624627 Free PMC article. Review.
Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.
Yokoyama U, Minamisawa S, Katayama A, Tang T, Suzuki S, Iwatsubo K, Iwasaki S, Kurotani R, Okumura S, Sato M, Yokota S, Hammond HK, Ishikawa Y. Yokoyama U, et al. Among authors: iwatsubo k. Circ Res. 2010 Jun 25;106(12):1882-92. doi: 10.1161/CIRCRESAHA.109.214924. Epub 2010 Apr 29. Circ Res. 2010. PMID: 20431059 Free PMC article.
67 results