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An evaluation of the FDA responder endpoint for IBS-C clinical trials: analysis of data from linaclotide Phase 3 clinical trials.
Macdougall JE, Johnston JM, Lavins BJ, Nelson LM, Williams VS, Carson RT, Shiff SJ, Shi K, Kurtz CB, Baird MJ, Currie MG, Lembo AJ. Macdougall JE, et al. Among authors: lembo aj. Neurogastroenterol Motil. 2013 Jun;25(6):481-6. doi: 10.1111/nmo.12089. Epub 2013 Feb 6. Neurogastroenterol Motil. 2013. PMID: 23384406 Clinical Trial.
The placebo effect in irritable bowel syndrome trials: a meta-analysis.
Patel SM, Stason WB, Legedza A, Ock SM, Kaptchuk TJ, Conboy L, Canenguez K, Park JK, Kelly E, Jacobson E, Kerr CE, Lembo AJ. Patel SM, et al. Among authors: lembo aj. Neurogastroenterol Motil. 2005 Jun;17(3):332-40. doi: 10.1111/j.1365-2982.2005.00650.x. Neurogastroenterol Motil. 2005. PMID: 15916620
Serum correlates of the placebo effect in irritable bowel syndrome.
Kokkotou E, Conboy LA, Ziogas DC, Quilty MT, Kelley JM, Davis RB, Lembo AJ, Kaptchuk TJ. Kokkotou E, et al. Among authors: lembo aj. Neurogastroenterol Motil. 2010 Mar;22(3):285-e81. doi: 10.1111/j.1365-2982.2009.01440.x. Epub 2009 Dec 22. Neurogastroenterol Motil. 2010. PMID: 20028464 Free PMC article. Clinical Trial.
Efficacy of linaclotide for patients with chronic constipation.
Lembo AJ, Kurtz CB, Macdougall JE, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Johnston JM. Lembo AJ, et al. Gastroenterology. 2010 Mar;138(3):886-95.e1. doi: 10.1053/j.gastro.2009.12.050. Epub 2010 Jan 4. Gastroenterology. 2010. PMID: 20045700 Clinical Trial.
Two randomized trials of linaclotide for chronic constipation.
Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, Shao JZ, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Eng P, Fox SM, Johnston JM. Lembo AJ, et al. N Engl J Med. 2011 Aug 11;365(6):527-36. doi: 10.1056/NEJMoa1010863. N Engl J Med. 2011. PMID: 21830967 Free article. Clinical Trial.
Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
Chey WD, Lembo AJ, Lavins BJ, Shiff SJ, Kurtz CB, Currie MG, MacDougall JE, Jia XD, Shao JZ, Fitch DA, Baird MJ, Schneier HA, Johnston JM. Chey WD, et al. Among authors: lembo aj. Am J Gastroenterol. 2012 Nov;107(11):1702-12. doi: 10.1038/ajg.2012.254. Am J Gastroenterol. 2012. PMID: 22986437 Clinical Trial.
250 results