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Systematic exploration of dual-acting modulators from a combined medicinal chemistry and biology perspective.
J Med Chem. 2013 Feb 14;56(3):1197-210. doi: 10.1021/jm301653f. Epub 2013 Jan 29.
J Med Chem. 2013.
PMID: 23281966
In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib.
Rolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M.
Rolf MG, et al. Among authors: hellawell cj.
Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
Pharmacol Res Perspect. 2015.
PMID: 26516587
Free PMC article.
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Relationship of serum markers of cartilage metabolism to imaging and clinical outcome measures of knee joint structure.
Berry PA, Maciewicz RA, Wluka AE, Downey-Jones MD, Forbes A, Hellawell CJ, Cicuttini FM.
Berry PA, et al. Among authors: hellawell cj.
Ann Rheum Dis. 2010 Oct;69(10):1816-22. doi: 10.1136/ard.2009.124420. Epub 2010 Jun 15.
Ann Rheum Dis. 2010.
PMID: 20551154
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Markers of bone formation and resorption identify subgroups of patients with clinical knee osteoarthritis who have reduced rates of cartilage loss.
Berry PA, Maciewicz RA, Cicuttini FM, Jones MD, Hellawell CJ, Wluka AE.
Berry PA, et al. Among authors: hellawell cj.
J Rheumatol. 2010 Jun;37(6):1252-9. doi: 10.3899/jrheum.091055. Epub 2010 Apr 15.
J Rheumatol. 2010.
PMID: 20395641
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