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Page 1
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials.
Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, Sinnis P, Scott RW, Greenbaum DC. Love MS, et al. Among authors: costanzo mj. Cell Host Microbe. 2012 Dec 13;12(6):815-23. doi: 10.1016/j.chom.2012.10.017. Cell Host Microbe. 2012. PMID: 23245326 Free PMC article.
De novo design of self-assembling foldamers that inhibit heparin-protein interactions.
Montalvo GL, Zhang Y, Young TM, Costanzo MJ, Freeman KB, Wang J, Clements DJ, Magavern E, Kavash RW, Scott RW, Liu D, Degrado WF. Montalvo GL, et al. Among authors: costanzo mj. ACS Chem Biol. 2014 Apr 18;9(4):967-75. doi: 10.1021/cb500026x. Epub 2014 Feb 11. ACS Chem Biol. 2014. PMID: 24491145 Free PMC article.
Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents.
Rubin H, Selwood T, Yano T, Weaver DG, Loughran HM, Costanzo MJ, Scott RW, Wrobel JE, Freeman KB, Reitz AB. Rubin H, et al. Among authors: costanzo mj. Bioorg Med Chem Lett. 2015 Jan 15;25(2):378-83. doi: 10.1016/j.bmcl.2014.11.020. Epub 2014 Nov 22. Bioorg Med Chem Lett. 2015. PMID: 25496770
Potent in vitro and in vivo antifungal activity of a small molecule host defense peptide mimic through a membrane-active mechanism.
Menzel LP, Chowdhury HM, Masso-Silva JA, Ruddick W, Falkovsky K, Vorona R, Malsbary A, Cherabuddi K, Ryan LK, DiFranco KM, Brice DC, Costanzo MJ, Weaver D, Freeman KB, Scott RW, Diamond G. Menzel LP, et al. Among authors: costanzo mj. Sci Rep. 2017 Jun 28;7(1):4353. doi: 10.1038/s41598-017-04462-6. Sci Rep. 2017. PMID: 28659617 Free PMC article.
Pyrroloisoquinoline antidepressants. 3. A focus on serotonin.
Maryanoff BE, Vaught JL, Shank RP, McComsey DF, Costanzo MJ, Nortey SO. Maryanoff BE, et al. Among authors: costanzo mj. J Med Chem. 1990 Oct;33(10):2793-7. doi: 10.1021/jm00172a018. J Med Chem. 1990. PMID: 2213832
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.
Costanzo MJ, Yabut SC, Zhang HC, White KB, de Garavilla L, Wang Y, Minor LK, Tounge BA, Barnakov AN, Lewandowski F, Milligan C, Spurlino JC, Abraham WM, Boswell-Smith V, Page CP, Maryanoff BE. Costanzo MJ, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2114-21. doi: 10.1016/j.bmcl.2008.01.093. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18272363
24 results