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Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells.
Folgiero V, Di Carlo SE, Bon G, Spugnini EP, Di Benedetto A, Germoni S, Pia Gentileschi M, Accardo A, Milella M, Morelli G, Bossi G, Mottolese M, Falcioni R. Folgiero V, et al. Among authors: mottolese m. Cell Death Dis. 2012 Dec 6;3(12):e440. doi: 10.1038/cddis.2012.179. Cell Death Dis. 2012. PMID: 23222510 Free PMC article.
Induction of ErbB-3 expression by alpha6beta4 integrin contributes to tamoxifen resistance in ERbeta1-negative breast carcinomas.
Folgiero V, Avetrani P, Bon G, Di Carlo SE, Fabi A, Nisticò C, Vici P, Melucci E, Buglioni S, Perracchio L, Sperduti I, Rosanò L, Sacchi A, Mottolese M, Falcioni R. Folgiero V, et al. Among authors: mottolese m. PLoS One. 2008 Feb 13;3(2):e1592. doi: 10.1371/journal.pone.0001592. PLoS One. 2008. PMID: 18270579 Free PMC article.
ATM kinase sustains HER2 tumorigenicity in breast cancer.
Stagni V, Manni I, Oropallo V, Mottolese M, Di Benedetto A, Piaggio G, Falcioni R, Giaccari D, Di Carlo S, Sperati F, Cencioni MT, Barilà D. Stagni V, et al. Among authors: mottolese m. Nat Commun. 2015 Apr 16;6:6886. doi: 10.1038/ncomms7886. Nat Commun. 2015. PMID: 25881002 Free article.
miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer.
Sacconi A, Biagioni F, Canu V, Mori F, Di Benedetto A, Lorenzon L, Ercolani C, Di Agostino S, Cambria AM, Germoni S, Grasso G, Blandino R, Panebianco V, Ziparo V, Federici O, Muti P, Strano S, Carboni F, Mottolese M, Diodoro M, Pescarmona E, Garofalo A, Blandino G. Sacconi A, et al. Among authors: mottolese m. Cell Death Dis. 2012 Nov 15;3(11):e423. doi: 10.1038/cddis.2012.160. Cell Death Dis. 2012. PMID: 23152059 Free PMC article.
Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer.
Sette G, Salvati V, Mottolese M, Visca P, Gallo E, Fecchi K, Pilozzi E, Duranti E, Policicchio E, Tartaglia M, Milella M, De Maria R, Eramo A. Sette G, et al. Among authors: mottolese m. Cell Death Dis. 2015 Aug 6;6(8):e1850. doi: 10.1038/cddis.2015.217. Cell Death Dis. 2015. PMID: 26247735 Free PMC article.
miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours.
Biagioni F, Bossel Ben-Moshe N, Fontemaggi G, Canu V, Mori F, Antoniani B, Di Benedetto A, Santoro R, Germoni S, De Angelis F, Cambria A, Avraham R, Grasso G, Strano S, Muti P, Mottolese M, Yarden Y, Domany E, Blandino G. Biagioni F, et al. Among authors: mottolese m. EMBO Mol Med. 2012 Nov;4(11):1214-29. doi: 10.1002/emmm.201201483. EMBO Mol Med. 2012. PMID: 23125021 Free PMC article.
Dual targeting of HER3 and MEK may overcome HER3-dependent drug-resistance of colon cancers.
Bon G, Loria R, Amoreo CA, Verdina A, Sperduti I, Mastrofrancesco A, Soddu S, Diodoro MG, Mottolese M, Todaro M, Stassi G, Milella M, De Maria R, Falcioni R. Bon G, et al. Among authors: mottolese m. Oncotarget. 2016 Aug 19;8(65):108463-108479. doi: 10.18632/oncotarget.11400. eCollection 2017 Dec 12. Oncotarget. 2016. PMID: 29312543 Free PMC article.
243 results