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Effects of cyclodextrin in two patients with Niemann-Pick Type C disease.
Matsuo M, Togawa M, Hirabaru K, Mochinaga S, Narita A, Adachi M, Egashira M, Irie T, Ohno K. Matsuo M, et al. Among authors: ohno k. Mol Genet Metab. 2013 Jan;108(1):76-81. doi: 10.1016/j.ymgme.2012.11.005. Epub 2012 Nov 15. Mol Genet Metab. 2013. PMID: 23218948
Corrigendum to "In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-pick type C disease" [Mol. Genet. Metab. (2016) 214-219].
Kondo Y, Tokumaru H, Ishitsuka Y, Matsumoto T, Taguchi M, Motoyama K, Higashi T, Arima H, Matsuo M, Higaki K, Ohno K, Irie T. Kondo Y, et al. Among authors: ohno k. Mol Genet Metab. 2017 Mar;120(3):296-297. doi: 10.1016/j.ymgme.2016.09.004. Epub 2016 Oct 10. Mol Genet Metab. 2017. PMID: 27733311 No abstract available.
Influence of Npc1 genotype on the toxicity of hydroxypropyl-β-cyclodextrin, a potentially therapeutic agent, in Niemann-Pick Type C disease models.
Tanaka Y, Ishitsuka Y, Yamada Y, Kondo Y, Takeo T, Nakagata N, Higashi T, Motoyama K, Arima H, Matsuo M, Higaki K, Ohno K, Irie T. Tanaka Y, et al. Among authors: ohno k. Mol Genet Metab Rep. 2014 Jan 11;1:19-30. doi: 10.1016/j.ymgmr.2013.12.003. eCollection 2014. Mol Genet Metab Rep. 2014. PMID: 27896072 Free PMC article.
In Vitro and In Vivo Evaluation of 6-O-α-Maltosyl-β-Cyclodextrin as a Potential Therapeutic Agent Against Niemann-Pick Disease Type C.
Yasmin N, Ishitsuka Y, Fukaura M, Yamada Y, Nakahara S, Ishii A, Kondo Y, Takeo T, Nakagata N, Motoyama K, Higashi T, Okada Y, Nishikawa J, Ichikawa A, Iohara D, Hirayama F, Higaki K, Ohno K, Matsuo M, Irie T. Yasmin N, et al. Among authors: ohno k. Int J Mol Sci. 2019 Mar 6;20(5):1152. doi: 10.3390/ijms20051152. Int J Mol Sci. 2019. PMID: 30845767 Free PMC article.
Efficacy of 2-Hydroxypropyl-β-cyclodextrin in Niemann-Pick Disease Type C Model Mice and Its Pharmacokinetic Analysis in a Patient with the Disease.
Tanaka Y, Yamada Y, Ishitsuka Y, Matsuo M, Shiraishi K, Wada K, Uchio Y, Kondo Y, Takeo T, Nakagata N, Higashi T, Motoyama K, Arima H, Mochinaga S, Higaki K, Ohno K, Irie T. Tanaka Y, et al. Among authors: ohno k. Biol Pharm Bull. 2015;38(6):844-51. doi: 10.1248/bpb.b14-00726. Biol Pharm Bull. 2015. PMID: 26027824 Free article.
Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C.
Yamada Y, Ishitsuka Y, Kondo Y, Nakahara S, Nishiyama A, Takeo T, Nakagata N, Motoyama K, Higashi T, Arima H, Kamei S, Shuto T, Kai H, Hayashino Y, Sugita M, Kikuchi T, Hirata F, Miwa T, Takeda H, Orita Y, Seki T, Ohta T, Kurauchi Y, Katsuki H, Matsuo M, Higaki K, Ohno K, Matsumoto S, Era T, Irie T. Yamada Y, et al. Among authors: ohno k. Br J Pharmacol. 2021 Jul;178(13):2727-2746. doi: 10.1111/bph.15464. Epub 2021 May 12. Br J Pharmacol. 2021. PMID: 33782944 Free article.
Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with Niemann-Pick disease type C and 3β-hydroxysteroid dehydrogenase deficiency.
Maekawa M, Shimada M, Ohno K, Togawa M, Nittono H, Iida T, Hofmann AF, Goto J, Yamaguchi H, Mano N. Maekawa M, et al. Among authors: ohno k. Ann Clin Biochem. 2015 Sep;52(Pt 5):576-87. doi: 10.1177/0004563214568871. Epub 2015 Jan 9. Ann Clin Biochem. 2015. PMID: 25575700
2,333 results