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Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.
Mansour WY, Bogdanova NV, Kasten-Pisula U, Rieckmann T, Köcher S, Borgmann K, Baumann M, Krause M, Petersen C, Hu H, Gatti RA, Dikomey E, Dörk T, Dahm-Daphi J. Mansour WY, et al. Among authors: gatti ra. Radiother Oncol. 2013 Jan;106(1):147-54. doi: 10.1016/j.radonc.2012.10.020. Epub 2012 Nov 28. Radiother Oncol. 2013. PMID: 23199656
MicroRNAs: new players in the DNA damage response.
Hu H, Gatti RA. Hu H, et al. Among authors: gatti ra. J Mol Cell Biol. 2011 Jun;3(3):151-8. doi: 10.1093/jmcb/mjq042. Epub 2010 Dec 23. J Mol Cell Biol. 2011. PMID: 21183529 Free PMC article. Review.
ATM is down-regulated by N-Myc-regulated microRNA-421.
Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. Hu H, et al. Among authors: gatti ra. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1506-11. doi: 10.1073/pnas.0907763107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080624 Free PMC article.
ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response.
Martin NT, Nakamura K, Davies R, Nahas SA, Brown C, Tunuguntla R, Gatti RA, Hu H. Martin NT, et al. Among authors: gatti ra. PLoS Genet. 2013 May;9(5):e1003505. doi: 10.1371/journal.pgen.1003505. Epub 2013 May 16. PLoS Genet. 2013. PMID: 23696749 Free PMC article.
Assaying Radiosensitivity of Ataxia-Telangiectasia.
Hu H, Nahas S, Gatti RA. Hu H, et al. Among authors: gatti ra. Methods Mol Biol. 2017;1599:1-11. doi: 10.1007/978-1-4939-6955-5_1. Methods Mol Biol. 2017. PMID: 28477107
A-TWinnipeg: Pathogenesis of rare ATM missense mutation c.6200C>A with decreased protein expression and downstream signaling, early-onset dystonia, cancer, and life-threatening radiotoxicity.
Nakamura K, Fike F, Haghayegh S, Saunders-Pullman R, Dawson AJ, Dörk T, Gatti RA. Nakamura K, et al. Among authors: gatti ra. Mol Genet Genomic Med. 2014 Jul;2(4):332-40. doi: 10.1002/mgg3.72. Epub 2014 Mar 13. Mol Genet Genomic Med. 2014. PMID: 25077176 Free PMC article.
314 results