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IP3 receptor type 2 deficiency is associated with a secretory defect in the pancreatic acinar cell and an accumulation of zymogen granules.
Orabi AI, Luo Y, Ahmad MU, Shah AU, Mannan Z, Wang D, Sarwar S, Muili KA, Shugrue C, Kolodecik TR, Singh VP, Lowe ME, Thrower E, Chen J, Husain SZ. Orabi AI, et al. Among authors: kolodecik tr. PLoS One. 2012;7(11):e48465. doi: 10.1371/journal.pone.0048465. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185258 Free PMC article.
The ryanodine receptor mediates early zymogen activation in pancreatitis.
Husain SZ, Prasad P, Grant WM, Kolodecik TR, Nathanson MH, Gorelick FS. Husain SZ, et al. Among authors: kolodecik tr. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14386-91. doi: 10.1073/pnas.0503215102. Epub 2005 Sep 26. Proc Natl Acad Sci U S A. 2005. PMID: 16186498 Free PMC article.
Low pH enhances connexin32 degradation in the pancreatic acinar cell.
Reed AM, Kolodecik T, Husain SZ, Gorelick FS. Reed AM, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1;307(1):G24-32. doi: 10.1152/ajpgi.00010.2014. Epub 2014 May 8. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24812055 Free PMC article.
Zymogen activation in a reconstituted pancreatic acinar cell system.
Thrower EC, Diaz de Villalvilla AP, Kolodecik TR, Gorelick FS. Thrower EC, et al. Among authors: kolodecik tr. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G894-902. doi: 10.1152/ajpgi.00373.2005. Epub 2005 Dec 8. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16339296 Free PMC article.
Vacuolar adenosine triphosphatase and pancreatic acinar cell function.
Gorelick FS, Shugrue CA, Kolodecik TR, Thrower EC. Gorelick FS, et al. Among authors: kolodecik tr. J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S18-21. doi: 10.1111/j.1440-1746.2006.04576.x. J Gastroenterol Hepatol. 2006. PMID: 16958663 Review.
The novel protein kinase C isoforms -delta and -epsilon modulate caerulein-induced zymogen activation in pancreatic acinar cells.
Thrower EC, Osgood S, Shugrue CA, Kolodecik TR, Chaudhuri AM, Reeve JR Jr, Pandol SJ, Gorelick FS. Thrower EC, et al. Among authors: kolodecik tr. Am J Physiol Gastrointest Liver Physiol. 2008 Jun;294(6):G1344-53. doi: 10.1152/ajpgi.00020.2008. Epub 2008 Apr 3. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18388183 Free PMC article.
Vacuolar ATPase regulates zymogen activation in pancreatic acini.
Waterford SD, Kolodecik TR, Thrower EC, Gorelick FS. Waterford SD, et al. Among authors: kolodecik tr. J Biol Chem. 2005 Feb 18;280(7):5430-4. doi: 10.1074/jbc.M413513200. Epub 2004 Dec 6. J Biol Chem. 2005. PMID: 15582989 Free PMC article.
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