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A novel function for FOXP3 in humans: intrinsic regulation of conventional T cells.
McMurchy AN, Gillies J, Gizzi MC, Riba M, Garcia-Manteiga JM, Cittaro D, Lazarevic D, Di Nunzio S, Piras IS, Bulfone A, Roncarolo MG, Stupka E, Bacchetta R, Levings MK. McMurchy AN, et al. Among authors: gillies j. Blood. 2013 Feb 21;121(8):1265-75. doi: 10.1182/blood-2012-05-431023. Epub 2012 Nov 20. Blood. 2013. PMID: 23169781 Free article.
Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.
McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK. McMurchy AN, et al. Among authors: gillies j. J Allergy Clin Immunol. 2010 Dec;126(6):1242-51. doi: 10.1016/j.jaci.2010.09.001. Epub 2010 Oct 30. J Allergy Clin Immunol. 2010. PMID: 21036387
Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease.
Cook L, Munier CML, Seddiki N, van Bockel D, Ontiveros N, Hardy MY, Gillies JK, Levings MK, Reid HH, Petersen J, Rossjohn J, Anderson RP, Zaunders JJ, Tye-Din JA, Kelleher AD. Cook L, et al. Among authors: gillies jk. J Allergy Clin Immunol. 2017 Dec;140(6):1592-1603.e8. doi: 10.1016/j.jaci.2017.02.015. Epub 2017 Mar 8. J Allergy Clin Immunol. 2017. PMID: 28283419 Free article.
Treg gene signatures predict and measure type 1 diabetes trajectory.
Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK. Pesenacker AM, et al. Among authors: gillies j. JCI Insight. 2019 Mar 21;4(6):e123879. doi: 10.1172/jci.insight.123879. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30730852 Free PMC article. Clinical Trial.
243 results