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Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation.
Fournier-Dit-Chabert J, Vinader V, Santos AR, Redondo-Horcajo M, Dreneau A, Basak R, Cosentino L, Marston G, Abdel-Rahman H, Loadman PM, Shnyder SD, Díaz JF, Barasoain I, Falconer RA, Pors K. Fournier-Dit-Chabert J, et al. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7693-6. doi: 10.1016/j.bmcl.2012.09.104. Epub 2012 Oct 10. Bioorg Med Chem Lett. 2012. PMID: 23103097
Synthesis and biological evaluation of colchicine B-ring analogues tethered with halogenated benzyl moieties.
Cosentino L, Redondo-Horcajo M, Zhao Y, Santos AR, Chowdury KF, Vinader V, Abdallah QM, Abdel-Rahman H, Fournier-Dit-Chabert J, Shnyder SD, Loadman PM, Fang WS, Díaz JF, Barasoain I, Burns PA, Pors K. Cosentino L, et al. Among authors: fournier dit chabert j. J Med Chem. 2012 Dec 27;55(24):11062-6. doi: 10.1021/jm301151t. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23176628
Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus.
Fournier Dit Chabert J, Marquez B, Neville L, Joucla L, Broussous S, Bouhours P, David E, Pellet-Rostaing S, Marquet B, Moreau N, Lemaire M. Fournier Dit Chabert J, et al. Bioorg Med Chem. 2007 Jul 1;15(13):4482-97. doi: 10.1016/j.bmc.2007.04.023. Epub 2007 Apr 19. Bioorg Med Chem. 2007. PMID: 17498961
Efficient access to 2-aryl-3-substituted benzo[b]thiophenes.
David E, Perrin J, Pellet-Rostaing S, Fournier dit Chabert J, Lemaire M. David E, et al. Among authors: fournier dit chabert j. J Org Chem. 2005 Apr 29;70(9):3569-73. doi: 10.1021/jo0500378. J Org Chem. 2005. PMID: 15844992