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Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.
Dubost E, Dumas N, Fossey C, Magnelli R, Butt-Gueulle S, Ballandonne C, Caignard DH, Dulin F, Sopkova de-Oliveira Santos J, Millet P, Charnay Y, Rault S, Cailly T, Fabis F. Dubost E, et al. Among authors: caignard dh. J Med Chem. 2012 Nov 26;55(22):9693-707. doi: 10.1021/jm300943r. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23102207 Free PMC article.
Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.
Prunier H, Rault S, Lancelot JC, Robba M, Renard P, Delagrange P, Pfeiffer B, Caignard DH, Misslin R, Guardiola-Lemaitre B, Hamon M. Prunier H, et al. Among authors: caignard dh. J Med Chem. 1997 Jun 6;40(12):1808-19. doi: 10.1021/jm960501o. J Med Chem. 1997. PMID: 9191957
3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans].
Comoy C, Marot C, Podona T, Baudin ML, Morin-Allory L, Guillaumet G, Pfeiffer B, Caignard DH, Renard P, Rettori MC, Adam G, Guardiola-Lemaitre B. Comoy C, et al. Among authors: caignard dh. J Med Chem. 1996 Oct 11;39(21):4285-98. doi: 10.1021/jm950861w. J Med Chem. 1996. PMID: 8863806
Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.
Mésangeau C, Pérès B, Descamps-François C, Chavatte P, Audinot V, Coumailleau S, Boutin JA, Delagrange P, Bennejean C, Renard P, Caignard DH, Berthelot P, Yous S. Mésangeau C, et al. Among authors: caignard dh. Bioorg Med Chem. 2010 May 15;18(10):3426-36. doi: 10.1016/j.bmc.2010.04.008. Epub 2010 Apr 7. Bioorg Med Chem. 2010. PMID: 20444610
94 results