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Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.
Dubost E, Dumas N, Fossey C, Magnelli R, Butt-Gueulle S, Ballandonne C, Caignard DH, Dulin F, Sopkova de-Oliveira Santos J, Millet P, Charnay Y, Rault S, Cailly T, Fabis F. Dubost E, et al. Among authors: ballandonne c. J Med Chem. 2012 Nov 26;55(22):9693-707. doi: 10.1021/jm300943r. Epub 2012 Nov 9. J Med Chem. 2012. PMID: 23102207 Free PMC article.
Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride.
Rochais C, Lecoutey C, Gaven F, Giannoni P, Hamidouche K, Hedou D, Dubost E, Genest D, Yahiaoui S, Freret T, Bouet V, Dauphin F, Sopkova de Oliveira Santos J, Ballandonne C, Corvaisier S, Malzert-Fréon A, Legay R, Boulouard M, Claeysen S, Dallemagne P. Rochais C, et al. Among authors: ballandonne c. J Med Chem. 2015 Apr 9;58(7):3172-87. doi: 10.1021/acs.jmedchem.5b00115. Epub 2015 Mar 31. J Med Chem. 2015. PMID: 25793650 Free article.
Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease.
Yahiaoui S, Hamidouche K, Ballandonne C, Davis A, de Oliveira Santos JS, Freret T, Boulouard M, Rochais C, Dallemagne P. Yahiaoui S, et al. Among authors: ballandonne c. Eur J Med Chem. 2016 Oct 4;121:283-293. doi: 10.1016/j.ejmech.2016.05.048. Epub 2016 May 26. Eur J Med Chem. 2016. PMID: 27266998
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
Lecoutey C, Hedou D, Freret T, Giannoni P, Gaven F, Since M, Bouet V, Ballandonne C, Corvaisier S, Malzert Fréon A, Mignani S, Cresteil T, Boulouard M, Claeysen S, Rochais C, Dallemagne P. Lecoutey C, et al. Among authors: ballandonne c. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3825-30. doi: 10.1073/pnas.1410315111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157130 Free PMC article.
Acute toxicity of 8 antidepressants: what are their modes of action?
Minguez L, Farcy E, Ballandonne C, Lepailleur A, Serpentini A, Lebel JM, Bureau R, Halm-Lemeille MP. Minguez L, et al. Among authors: ballandonne c. Chemosphere. 2014 Aug;108:314-9. doi: 10.1016/j.chemosphere.2014.01.057. Epub 2014 Feb 14. Chemosphere. 2014. PMID: 24534154
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